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Annual Reviews по журналам "Annual Review of Cell and Developmental Biology"

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  • Annaert Wim; De Strooper Bart (Annual Reviews, 2002-11-01)
    ▪ Abstract  The amyloid precursor protein and the proteases cleaving this protein are important players in the pathogenesis of Alzheimer's disease via the generation of the amyloid peptide. Physiologically, the amyloid ...
  • Belvin Marcia P.; Anderson Kathryn V. (Annual Reviews, 1996-11-01)
    ▪ Abstract  The Toll-Dorsal pathway in Drosophila and the interleukin-1 receptor (IL-1R)-NF-κB pathway in mammals are homologous signal transduction pathways that mediate several different biological responses. In Drosophila, ...
  • Sylvester Anne W.; Smith Laurie; Freeling Michael (Annual Reviews, 1996-11-01)
    ▪ Abstract  Leaves are produced repeatedly from the shoot apical meristem of plants. Molecular and cellular evidence show that identity of the leaf and its parts is acquired progressively and that the underlying process ...
  • Engqvist-Goldstein Åsa E.Y.; Drubin David G. (Annual Reviews, 2003-11-01)
    ▪ Abstract  Internalization of receptors, lipids, pathogens, and other cargo at the plasma membrane involves several different pathways and requires coordinated interactions between a variety of protein and lipid molecules. ...
  • Luo Liqun (Annual Reviews, 2002-11-01)
    ▪ Abstract  The actin cytoskeleton plays a major role in morphological development of neurons and in structural changes of adult neurons. This article reviews the myriad functions of actin and myosin in axon initiation, ...
  • Ayscough Kathryn R.; Drubin David G. (Annual Reviews, 1996-11-01)
    ▪ Abstract  Three of the most important questions concerning actin function are: (a) How does actin structure relate to actin function? (b) How does each of the numerous proteins that interact with actin contribute to actin ...
  • Schafer D. A.; Schroer T. A. (Annual Reviews, 1999-11-01)
    ▪ Abstract  Actin-related proteins (Arps) participate in a diverse array of cellular processes. They modulate assembly of conventional actin, contribute to microtubule-based motility catalyzed by dynein, and serve as ...
  • Owen David J.; Collins Brett M.; Evans Philip R. (Annual Reviews, 2004-11-01)
    ▪ Abstract  Clathrin-coated vesicles (CCVs) are responsible for the transport of proteins between various compartments of the secretory and endocytic systems. Clathrin forms a scaffold around these vesicles that is linked ...
  • Kirchhausen Tomas (Annual Reviews, 1999-11-01)
    ▪ Abstract  Clathrin-based systems are responsible for a large portion of vesicular traffic originating from the plasma membrane and the trans-Golgi network that reaches the endosomal compartment. The assembly of cytosolic ...
  • Bershadsky Alexander D.; Balaban Nathalie Q.; Geiger Benjamin (Annual Reviews, 2003-11-01)
    ▪ Abstract  The conversion of physical signals, such as contractile forces or external mechanical perturbations, into chemical signaling events is a fundamental cellular process that occurs at cell–extracellular matrix ...
  • Hwang Cheng-Shine; Loftus Thomas M.; Mandrup Susanne; Lane M. Daniel (Annual Reviews, 1997-11-01)
    ▪ Abstract  Adipose tissue has long been known to house the largest energy reserves in the animal body. Recent research indicates that in addition to this role, the adipocyte functions as a global regulator of energy ...
  • Raff Martin (Annual Reviews, 2003-11-01)
    ▪ Abstract  There has been unprecedented recent interest in stem cells, mainly because of the hope they offer for cell therapy. Adult stem cells are an attractive source of cells for therapy, especially in view of the ...
  • McCullen Colleen A.; Binns Andrew N. (Annual Reviews, 2006-11-01)
    Abstract Host recognition and macromolecular transfer of virulence-mediating effectors represent critical steps in the successful transformation of plant cells by Agrobacterium tumefaciens. This review focuses on bacterial ...
  • Schmidt Jennifer V.; Bradfield Christopher A. (Annual Reviews, 1996-11-01)
    ▪ Abstract  The aryl hydrocarbon (Ah) receptor has occupied the attention of toxicologists for over two decades. Interest arose from the early observation that this soluble protein played key roles in the adaptive metabolic ...
  • Glotzer Michael (Annual Reviews, 2001-11-01)
    ▪ Abstract  Cytokinesis creates two daughter cells endowed with a complete set of chromosomes and cytoplasmic organelles. This conceptually simple event is mediated by a complex and dynamic interplay between the microtubules ...
  • Baskin Tobias I. (Annual Reviews, 2005-11-01)
    Abstract Plants shape their organs with a precision demanded by optimal function; organ shaping requires control over cell wall expansion anisotropy. Focusing on multicellular organs, I survey the occurrence of expansion ...
  • Collier R. John; Young John A.T. (Annual Reviews, 2003-11-01)
    ▪ Abstract  Anthrax toxin consists of three nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells. One of these proteins, protective antigen (PA), ...
  • Cosgrove Daniel J. (Annual Reviews, 1997-11-01)
    ▪ Abstract  Growing plant cells are shaped by an extensible wall that is a complex amalgam of cellulose microfibrils bonded noncovalently to a matrix of hemicelluloses, pectins, and structural proteins. Cellulose is ...
  • Henikoff Steven; Ahmad Kami (Annual Reviews, 2005-11-01)
    Abstract Chromatin can be differentiated by the deposition of variant histones at centromeres, active genes, and silent loci. Variant histones are assembled into nucleosomes in a replication-independent manner, in contrast ...
  • Cowan Carrie R.; Hyman Anthony A. (Annual Reviews, 2004-11-01)
    ▪ Abstract  The one-cell Caenorhabditis elegans embryo divides asymmetrically into a larger and smaller blastomere, each with a different fate. How does such asymmetry arise? The sperm-supplied centrosome establishes an ...