An 80-yr-old man with advanced gastric cancer was admitted on September 10, 1982. He received no surgery owing to a moderate attack of bronchial asthma, hypertension and cardiac, pulmonary and renal function disturbances. Chemotherapy was started after discharge. The treatment regimen was the oral administration of 5-fluorouracil tablets at a dose of 200 mg a day, every day. Endoscopic examination 10 weeks after the initiation of chemotherapy revealed complete regression of the tumor and the biopsy specimen revealed no cancer cells. Since then, X-ray and endoscopic examination have been performed every two to three months. The patient is still well without relapse of the disease.