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Автор NAKAJIMA, TAKASHI
Автор OKAZAKI, NOBUO
Автор MORINAGA, SHOJIROH
Автор TSUMURAYA, MASARU
Автор SHIMOSATO, YUKIO
Автор SAIKI, SHIGEKI
Дата выпуска 1985
dc.description A rare case of rectal carcinoma with a high serum alpha-fetoprotein (AFP) level (maximum, 6,983 ng/ml) is reported. The histology of the primary tumor was adenosquamous carcinoma, the major component being moderately to poorly differentiated adenocarcinoma. Immunohistochemically, a few AFP-positive cells were identified in the primary tumor. However, numerous AFP-positive cells were observed in metastatic tumors in the liver and lungs at autopsy, which were histologically undifferentiated carcinoma with marked pleomorphism. Furthermore, components of adenocarcinoma were present in the metastatic tumors at various sites, and components of squamous cell carcinoma were seen only in the pelvic cavity. To our knowledge, this is the first case of rectal carcinoma with verified AFP production by the tumor cells.
Формат application.pdf
Издатель Oxford University Press
Копирайт © Oxford University Press
Тема Rectal carcinoma
Тема Adenosquamous carcinoma
Тема Alpha-fetoprotein
Тема Immunohistochemistry
Тема Case Reports
Название A Case of Alpha-Fetoprotein-Producing Rectal Carcinoma
Тип case-report
Electronic ISSN 1465-3621
Print ISSN 0368-2811
Журнал Japanese Journal of Clinical Oncology
Том 15
Первая страница 679
Последняя страница 685
Аффилиация Pathology Division, National Cancer Center Research InstituteTokyo
Аффилиация OKAZAKI NOBUO; Internal Medicine, National Cancer Center Hospital
Аффилиация SAIKI SHIGEKI; Pathology Section, St. Luke's International Hospital
Выпуск 4

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