Автор |
Couser, William G. |
Автор |
Abrass, Christine K. |
Дата выпуска |
1988 |
dc.description |
Membranous nephropathy is the most common cause of idiopathic nephrotic syndrome in adults. Recent studies of the pathogenesis of the sub-epithelial glomerular immune deposits that characterize this disease have revealed new mechanisms of glomerular immune deposit formation involving cell surface antigens and have documented the role of the C5b-9 membrane attack complex of complement in mediating renal injury. Understanding these mechanisms may help us understand the pathogenesis of several other immune-mediated diseases and has implications for possible therapeutic interventions in MN. |
Формат |
application.pdf |
Издатель |
Annual Reviews |
Копирайт |
Annual Reviews |
Название |
Pathogenesis of Membranous Nephropathy |
DOI |
10.1146/annurev.me.39.020188.002505 |
Print ISSN |
0066-4219 |
Журнал |
Annual Review of Medicine |
Том |
39 |
Первая страница |
517 |
Последняя страница |
530 |
Аффилиация |
Couser, William G.; Division of Nephrology, Department of Medicine, University of Washington, and the Veterans Administration Medical Center, Seattle, Washington 98195 |