| Автор | Fick, M.D, Godela M. |
| Автор | Gabow, M.D, Patricia A. |
| Дата выпуска | 1994 |
| dc.description | ▪ Abstract At least two different genes, which have been mapped to chromosomes 4 and 16, cause autosomal dominant polycystic kidney disease, a disorder with renal and extrarenal manifestations. Although gene-linkage testing is possible, the disease is diagnosed mainly through ultrasonography. Renal disease is characterized clinically by hypertension, acute and chronic pain, and variable progression to end-stage renal disease. Extrarenal manifestations include liver cysts, which may lead to complications; ruptured intracranial aneurysms; cardiac valvular disease; colonic diverticula; and inguinal hernias. Disease management is directed at minimizing and treating the complications of this illness. |
| Формат | application.pdf |
| Издатель | Annual Reviews |
| Копирайт | Annual Reviews |
| Название | NATURAL HISTORY OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE |
| DOI | 10.1146/annurev.med.45.1.23 |
| Print ISSN | 0066-4219 |
| Журнал | Annual Review of Medicine |
| Том | 45 |
| Первая страница | 23 |
| Последняя страница | 29 |
| Аффилиация | Fick, M.D, Godela M.; University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, Colorado 80262 |
