The 17-item Duke Health Profile (DUKE) was developed as a refined version of the 63-item Duke-UNC Health Profile (DUHP) using a methodology based upon a balanced clinical and statistical rationale. The result is a brief, valid functional health measure with 10 scales that compares well with the MOS Shortform and the COOP Charts. In addition to the five constructs (ambulation, emotional symptoms, activities with friends or relatives, health perception, and pain) which are measured by all three of the instruments, the DUKE quantitates cognition, social self-esteem, confinement, and somatic symptoms other than pain.