| Автор | Hayakawa, Makoto |
| Автор | Morise, Kimitomo |
| Автор | Chin, Kensho |
| Автор | Sugihara, Makoto |
| Автор | Morooka, Yutaka |
| Автор | Maeda, Hiroshi |
| Автор | Hattori, Tastsuo |
| Автор | Saito, Hidehiko |
| Дата выпуска | 1994 |
| dc.description | Thirty-four patients with advanced gastric cancer were treated with combination chemotherapy employing Tegafur-Uracil (UFT), etoposide, Adriamycin, and Cisplatinum (CDDP) (UFT-EAP therapy). An objective partial response was obtained in 16 patients (47%) and the median duration of remission was 12.2 months. The 50% survival time for all 34 patients was 10 months. Patients with moderately or well differentiated adenocarcinoma responded well (13/19, 68%), while those with undifferentiated adenocarcinoma showed a poor response (3/15, 20%). Six responding patients were noted to have no evidence of viable cancer at the primary site by endoscopic biopsy, and underwent gastrectomies. The resected specimens showed complete disappearances of the primary tumors in four patients. The median survival time for the patients receiving gastrectomies was 24 months. The regimen was very well tolerated, apart from moderate bone marrow suppression. Our results suggest that patients with advanced gastric cancer can be effectively treated with UFT-EAP chemotherapy |
| Формат | application.pdf |
| Издатель | Oxford University Press |
| Копирайт | © Oxford University Press |
| Тема | Combination chemotherapy |
| Тема | Gastric cancer with UFT |
| Тема | EAP chemotherapy |
| Тема | Articles |
| Название | Combination Chemotherapy with Tegafur-Uracil (UFT), Etoposide, Adriamycin and Cisplatinum (UFT-EAP) for Advanced Gastric Cancer |
| Тип | research-article |
| Electronic ISSN | 1465-3621 |
| Print ISSN | 0368-2811 |
| Журнал | Japanese Journal of Clinical Oncology |
| Том | 24 |
| Первая страница | 282 |
| Последняя страница | 288 |
| Аффилиация | Hayakawa Makoto; Department of Gastroenterology, Meitetsu Hospital |
| Аффилиация | Morise Kimitomo; First Department of Internal Medicine, Nagoya University School of Medicine |
| Аффилиация | Chin Kensho; Department of Gastroenterology, Meitetsu Hospital |
| Аффилиация | Sugihara Makoto; Department of Gastroenterology, Meitetsu Hospital |
| Аффилиация | Morooka Yutaka; Department of Gastroenterology, Meitetsu Hospital |
| Аффилиация | Maeda Hiroshi; Department of Gastroenterology, Meitetsu Hospital |
| Аффилиация | Hattori Tastsuo; Department of Surgery, Japanese Red Cross First Nagoya Hospital |
| Аффилиация | Saito Hidehiko; First Department of Internal Medicine, Nagoya University School of Medicine |
| Выпуск | 5 |
