| Автор | Mattick, John S. |
| Дата выпуска | 2002 |
| dc.description | ▪ Abstract Twitching motility is a flagella-independent form of bacterial translocation over moist surfaces. It occurs by the extension, tethering, and then retraction of polar type IV pili, which operate in a manner similar to a grappling hook. Twitching motility is equivalent to social gliding motility in Myxococcus xanthus and is important in host colonization by a wide range of plant and animal pathogens, as well as in the formation of biofilms and fruiting bodies. The biogenesis and function of type IV pili is controlled by a large number of genes, almost 40 of which have been identified in Pseudomonas aeruginosa. A number of genes required for pili assembly are homologous to genes involved in type II protein secretion and competence for DNA uptake, suggesting that these systems share a common architecture. Twitching motility is also controlled by a range of signal transduction systems, including two-component sensor-regulators and a complex chemosensory system. |
| Формат | application.pdf |
| Издатель | Annual Reviews |
| Копирайт | Annual Reviews |
| Название | TYPE IV PILI AND TWITCHING MOTILITY |
| DOI | 10.1146/annurev.micro.56.012302.160938 |
| Print ISSN | 0066-4227 |
| Журнал | Annual Review of Microbiology |
| Том | 56 |
| Первая страница | 289 |
| Последняя страница | 314 |
| Аффилиация | Mattick, John S.; ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane Qld. 4072, Australia; e-mail: j.mattick@imb.uq.edu.au |
