| Автор | Liti, Gianni |
| Автор | Louis, Edward J. |
| Дата выпуска | 2005 |
| dc.description | Abstract Recent sequencing efforts and experiments have advanced our understanding of genome evolution in yeasts, particularly the Saccharomyces yeasts. The ancestral genome of the Saccharomyces sensu stricto complex has been subject to both whole-genome duplication, followed by massive sequence loss and divergence, and segmental duplication. In addition the subtelomeric regions are subject to further duplications and rearrangements via ectopic exchanges. Translocations and other gross chromosomal rearrangements that break down syntenic relationships occur; however, they do not appear to be a driving force of speciation. Analysis of single genomes has been fruitful for hypothesis generation such as the whole-genome duplication, but comparative genomics between close and more distant species has proven to be a powerful tool in testing these hypotheses as well as elucidating evolutionary processes acting on the genome. Future work on population genomics and experimental evolution will keep yeast at the forefront of studies in genome evolution. |
| Формат | application.pdf |
| Издатель | Annual Reviews |
| Копирайт | Annual Reviews |
| Название | YEAST EVOLUTION AND COMPARATIVE GENOMICS |
| DOI | 10.1146/annurev.micro.59.030804.121400 |
| Print ISSN | 0066-4227 |
| Журнал | Annual Review of Microbiology |
| Том | 59 |
| Первая страница | 135 |
| Последняя страница | 153 |
| Аффилиация | Liti, Gianni; Institute of Genetics, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom; email: gianni.liti@nottingham.ac.uk , ed.louis@nottingham.ac.uk |
