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Annual Reviews по журналам "Annual Review of Cell and Developmental Biology"

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  • A CELL BIOLOGICAL PERSPECTIVE ON ALZHEIMER'S DISEASE
    Annaert Wim; De Strooper Bart (Annual Reviews, 2002-11-01)
    ▪ Abstract  The amyloid precursor protein and the proteases cleaving this protein are important players in the pathogenesis of Alzheimer's disease via the generation of the amyloid peptide. Physiologically, the amyloid ...
  • A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway
    Belvin Marcia P.; Anderson Kathryn V. (Annual Reviews, 1996-11-01)
    ▪ Abstract  The Toll-Dorsal pathway in Drosophila and the interleukin-1 receptor (IL-1R)-NF-κB pathway in mammals are homologous signal transduction pathways that mediate several different biological responses. In Drosophila, ...
  • ACQUISITION OF IDENTITY IN THE DEVELOPING LEAF
    Sylvester Anne W.; Smith Laurie; Freeling Michael (Annual Reviews, 1996-11-01)
    ▪ Abstract  Leaves are produced repeatedly from the shoot apical meristem of plants. Molecular and cellular evidence show that identity of the leaf and its parts is acquired progressively and that the underlying process ...
  • ACTIN ASSEMBLY AND ENDOCYTOSIS: From Yeast to Mammals
    Engqvist-Goldstein Åsa E.Y.; Drubin David G. (Annual Reviews, 2003-11-01)
    ▪ Abstract  Internalization of receptors, lipids, pathogens, and other cargo at the plasma membrane involves several different pathways and requires coordinated interactions between a variety of protein and lipid molecules. ...
  • ACTIN CYTOSKELETON REGULATION IN NEURONAL MORPHOGENESIS AND STRUCTURAL PLASTICITY
    Luo Liqun (Annual Reviews, 2002-11-01)
    ▪ Abstract  The actin cytoskeleton plays a major role in morphological development of neurons and in structural changes of adult neurons. This article reviews the myriad functions of actin and myosin in axon initiation, ...
  • ACTIN: General Principles from Studies in Yeast
    Ayscough Kathryn R.; Drubin David G. (Annual Reviews, 1996-11-01)
    ▪ Abstract  Three of the most important questions concerning actin function are: (a) How does actin structure relate to actin function? (b) How does each of the numerous proteins that interact with actin contribute to actin ...
  • ACTIN-RELATED PROTEINS
    Schafer D. A.; Schroer T. A. (Annual Reviews, 1999-11-01)
    ▪ Abstract  Actin-related proteins (Arps) participate in a diverse array of cellular processes. They modulate assembly of conventional actin, contribute to microtubule-based motility catalyzed by dynein, and serve as ...
  • ADAPTORS FOR CLATHRIN COATS: Structure and Function
    Owen David J.; Collins Brett M.; Evans Philip R. (Annual Reviews, 2004-11-01)
    ▪ Abstract  Clathrin-coated vesicles (CCVs) are responsible for the transport of proteins between various compartments of the secretory and endocytic systems. Clathrin forms a scaffold around these vesicles that is linked ...
  • ADAPTORS FOR CLATHRIN-MEDIATED TRAFFIC
    Kirchhausen Tomas (Annual Reviews, 1999-11-01)
    ▪ Abstract  Clathrin-based systems are responsible for a large portion of vesicular traffic originating from the plasma membrane and the trans-Golgi network that reaches the endosomal compartment. The assembly of cytosolic ...
  • ADHESION-DEPENDENT CELL MECHANOSENSITIVITY
    Bershadsky Alexander D.; Balaban Nathalie Q.; Geiger Benjamin (Annual Reviews, 2003-11-01)
    ▪ Abstract  The conversion of physical signals, such as contractile forces or external mechanical perturbations, into chemical signaling events is a fundamental cellular process that occurs at cell–extracellular matrix ...
  • ADIPOCYTE DIFFERENTIATION AND LEPTIN EXPRESSION
    Hwang Cheng-Shine; Loftus Thomas M.; Mandrup Susanne; Lane M. Daniel (Annual Reviews, 1997-11-01)
    ▪ Abstract  Adipose tissue has long been known to house the largest energy reserves in the animal body. Recent research indicates that in addition to this role, the adipocyte functions as a global regulator of energy ...
  • ADULT STEM CELL PLASTICITY: Fact or Artifact?
    Raff Martin (Annual Reviews, 2003-11-01)
    ▪ Abstract  There has been unprecedented recent interest in stem cells, mainly because of the hope they offer for cell therapy. Adult stem cells are an attractive source of cells for therapy, especially in view of the ...
  • Agrobacterium tumefaciens and Plant Cell Interactions and Activities Required for Interkingdom Macromolecular Transfer
    McCullen Colleen A.; Binns Andrew N. (Annual Reviews, 2006-11-01)
    Abstract Host recognition and macromolecular transfer of virulence-mediating effectors represent critical steps in the successful transformation of plant cells by Agrobacterium tumefaciens. This review focuses on bacterial ...
  • AH RECEPTOR SIGNALING PATHWAYS
    Schmidt Jennifer V.; Bradfield Christopher A. (Annual Reviews, 1996-11-01)
    ▪ Abstract  The aryl hydrocarbon (Ah) receptor has occupied the attention of toxicologists for over two decades. Interest arose from the early observation that this soluble protein played key roles in the adaptive metabolic ...
  • ANIMAL CELL CYTOKINESIS
    Glotzer Michael (Annual Reviews, 2001-11-01)
    ▪ Abstract  Cytokinesis creates two daughter cells endowed with a complete set of chromosomes and cytoplasmic organelles. This conceptually simple event is mediated by a complex and dynamic interplay between the microtubules ...
  • ANISOTROPIC EXPANSION OF THE PLANT CELL WALL
    Baskin Tobias I. (Annual Reviews, 2005-11-01)
    Abstract Plants shape their organs with a precision demanded by optimal function; organ shaping requires control over cell wall expansion anisotropy. Focusing on multicellular organs, I survey the occurrence of expansion ...
  • ANTHRAX TOXIN
    Collier R. John; Young John A.T. (Annual Reviews, 2003-11-01)
    ▪ Abstract  Anthrax toxin consists of three nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells. One of these proteins, protective antigen (PA), ...
  • ASSEMBLY AND ENLARGEMENT OF THE PRIMARY CELL WALL IN PLANTS
    Cosgrove Daniel J. (Annual Reviews, 1997-11-01)
    ▪ Abstract  Growing plant cells are shaped by an extensible wall that is a complex amalgam of cellulose microfibrils bonded noncovalently to a matrix of hemicelluloses, pectins, and structural proteins. Cellulose is ...
  • ASSEMBLY OF VARIANT HISTONES INTO CHROMATIN
    Henikoff Steven; Ahmad Kami (Annual Reviews, 2005-11-01)
    Abstract Chromatin can be differentiated by the deposition of variant histones at centromeres, active genes, and silent loci. Variant histones are assembled into nucleosomes in a replication-independent manner, in contrast ...
  • ASYMMETRIC CELL DIVISION IN C. ELEGANS: Cortical Polarity and Spindle Positioning
    Cowan Carrie R.; Hyman Anthony A. (Annual Reviews, 2004-11-01)
    ▪ Abstract  The one-cell Caenorhabditis elegans embryo divides asymmetrically into a larger and smaller blastomere, each with a different fate. How does such asymmetry arise? The sperm-supplied centrosome establishes an ...