Oxford University Press по журналам "Nucleic Acids Research"
Отображаемые элементы 1-20 из 10266
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(Oxford University Press, 1982-10-01)13C T1's and NOE's have been measured for all protonated carbons of 2′-deoxy-D-ribose (2′-d-ribose), 2′-deoxyadenosine-5′-monophosphate (5′-dAMP), thymidine-3′-monophosphate (3′-TMP) and thymidine-5′-monophosphate (5′-TMP) ...
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(Oxford University Press, 1987-08-01)The amino protons of 15N-labeled DNA were studied as a possible structural probe in NMR investigations of the interaction of DNA with various ligands. Since the inino protons are located in the center of the double helix, ...
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(Oxford University Press, 1981-06-01)The 49 nucleotide fragment derived from the 3′ end of 16S rRNA by cloacin DF13, is not cleaved by ribonuclease T1 at a guanosine residue that is present at 27 nucleotides from the 3′ terminus (position 1515 in 16S rRNA). ...
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(Oxford University Press, 1984-01-01)We have developed a package of programs to create, maintain and manipulate a data base of 16S rRNA oligonucleotide catalog data. For the first time all the published catalog data is brought together in one olace in a readily ...
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(Oxford University Press, 1987-01-01)
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(Oxford University Press, 1979)In this study 1H NMR has been used to investigate the conformational state of DNA in nucleosome core particles. The nucleosome core particles exhibit partially resolved low field (10–15 ppm) spectra due to imino protons ...
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(Oxford University Press, 1977-06-01)The hydrogen-bonded NH resonances of Baker's yeast tRNAPhe in H20 solution with Mg++ have been measured by a 360 MHz spectrometer at 23°C. Totally, fifteen peaks and one shoulder can be resolved which represent 25±1 protons. ...
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(Oxford University Press, 1979-06-01)The molecular conformations of naturally occurring 2-thio-pyrimidine nucleosides (5-methylaminomethyl-2-thiouridine, 5-methoxycarbonylmethyl-2-thiouridine and 2-thiocytidine) and 5′-mononucleotides (5-methylaminomethyl-2 ...
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(Oxford University Press, 1983-07-01)Comparative 1H NMR and optical studies of the interaction between poly (dA-dT), ethidium bromide (Et) and ethidium dimer (Et2) in 0.7 M NaCl are reported as a function of the temperature. Denaturation of the complexes ...
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(Oxford University Press, 1987-06-01)A comparison is presented of the imino proton NMR spectra of the double stranded octamer d(GCGTTGCG).d(CGCAACGC) and the same octamer in which the two central thymine residues occur as a cis-syn thymine dimer. Except for ...
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1H-NMR study of the interaction of daunomycin with B-DNA helices of methylated oligodeoxynucleotides(Oxford University Press, 1984-08-01)The interaction of daunomycin with B-DNA double helices of several methylated deoxynucleotides, d(C-G-m5C-G), d(m5C-G-C-G) d(C-G-m5C-G-C-G) and d(m5C-G-C-G-m5C-G) in solution was investigated by 1H-NMR spectroscopy at 500 ...
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(Oxford University Press, 1994-04-01)Synthesis of 1,N6-etheno-2′-deoxyadenoslne, 3,N4-etheno-2′-deoxycytldlne, and further chemistry on both deoxy and ribo series etheno nucleosides produces the corresponding phosphoramidites. These novel phosphoramidites are ...
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(Oxford University Press, 1987-11-01)Methods for increasing the transient level of expression of transfected DNA in cultured Drosophila cells have been examined. Here we show that cells exposed to the steroid hormone 20-hydroxyecdysone for 48h prior to ...
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(Oxford University Press, 1976-04-01)Detritylation of 2′3′-O-carbonyl-5′-O-trityluridine (Ia) with ethereal hydrogen chloride affords 2′,3′-O-carbonyluridine (Ib; 83%) which is converted by mesylation to the 5′-mesylcarbonate Ic (75%). Reaction of compound ...
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(Oxford University Press, 1984-02-01)It is shown that 2′,3′-dideoxy-3′-aminonucleoside 5′-tri-phosphates with adenine, guanine, cytosine and thymine bases are effective inhibitors of DNA polymerase I, calf thymus DNA polymerase α and rat liver DNA polymerase ...
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(Oxford University Press, 1978-12-01)The substrate specificity of 2′-deoxy-2′-substituted uridines and their 5′-phosphates towards thymidylate synthetase from Escherichia coli K12 was investigated. Besides the natural substrate 2′-deoxyuridine-5′-phosphate ...
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(Oxford University Press, 1979-03-01)dUfITP was tested as substrate in the E.coli RNA polymerase system using poly(dAT) as template. dUfITP could replace UTP when Mn++ was utilized as divalent cation instead of Mg++. The level of transcription with the fluoro ...
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(Oxford University Press, 1987-02-01)The synthesis of two new analogs of 2′-deoxyguanosine, 6-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1H-pyrrolo[3,2-c]pyridin-4(5H)-one (8) and 6-amino-1-β-D-arabinofuranosyl-1H-pyrrolo[3,2-c]-pyridin-4(5H)-one (13) has ...
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(Oxford University Press, 1987-09-01)The unnatural oligonucleotide α-d(TCTAAAC) was synthesized and was found more resistant towards endonucleases than its β-analog. 2D-NMR experiments allowed the assignment of all non-exchangeable aromatic and sugar protons ...
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(Oxford University Press, 1991-05-01)We describe the synthesis of 2′-O-methyl, 2′-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides and demonstrate their utility as Inhibitors of the in vitro U7 snRNP-dependent mRNA processing event. ...
Отображаемые элементы 1-20 из 10266