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Oxford University Press по журналам "The Journals of Gerontology Series A: Biological Sciences and Medical Sciences"

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  • Caprioli Antonio; Markowska Alicja L.; Olton David S. (The Gerontological Society of America, 1995-07-01)
    Chronic Acetyl-L-Carnitine (ALCAR) treatment prevents some age-related memory impairment. The present experiment examined the effects of aging and ALCAR in Fischer 344 rats on retention of spatial discrimination test in a ...
  • Неизвестный автор (The Gerontological Society of America, 1995-05-01)
  • Teramoto Shinji; Fukuchi Yoshinosuke; Nagase Takahide; Matsuse Takeshi; Orimo Hajime (The Gerontological Society of America, 1995-01-01)
    To elucidate the influence of age on ventilation components during exercise, we investigated the change in fractional contribution of abdomen or thorax during exercise in 12 elderly (71.9 ± 5.3, mean ± SD years) and 12 ...
  • Ades Philip A.; Waldmann Mary L.; Gillespie Colin (The Gerontological Society of America, 1995-01-01)
    Background. This study compared the effects of a formal exercise conditioning program of 3 and 12 months duration to spontaneous recovery in a population of older, post-coronary event patients. Methods. Indices of peak ...
  • Dudas Steven P.; Arking Robert (The Gerontological Society of America, 1995-05-01)
    The extended longevity phenotype (ELP) characteristic of our selected long-lived strain of Drosophila is brought about by a delayed onset of senescence which occurs in the young (5–7 day) adult. Genetically competent animals ...
  • Carmichael Crista M.; McGue Matt (The Gerontological Society of America, 1995-07-01)
    A cross-sectional twin design was used to study the developmental nature of genetic and environmental influences on height, weight, and body mass index. The sample of same-sex adult male and female twins consisted of 586 ...
  • Rossiter-Fornoff Jane E.; Wolf Steven L.; Wolfson Leslie I.; Buchner David M.; (The Gerontological Society of America, 1995-11-01)
    Background. Two simple balance scales comprising three or four familiar tests of static balance were developed, and their validity and reliability are described. The scales were such that the relative difficulties of the ...
  • Grossmann Angelika; Rabinovitch Peter S.; Kavanagh Terrance J.; Jinneman John C.; Gilliland Lisa K.; Ledbetter Jeffrey A.; Kanner Steven B. (The Gerontological Society of America, 1995-07-01)
    Cross-linking of the T-cell receptor (CD3) induces activation of tyrosine kinases and the subsequent phosphorylation of intracellular protein substrates. We examined whether early events in signal transduction through CD3 ...
  • Tsuji Ichiro; Minami Yuko; Fukao Akira; Hisamichi Shigeru; Asano Hirotake; Sato Makito (The Gerontological Society of America, 1995-05-01)
    Background. This study estimated the active life expectancy (ALE) among the elderly in a Japanese urban society to determine whether or not the Japanese live long lives at the expense of life quality. Methods. Survival and ...
  • Sims Richard V.; Hauser Raymond J.; Adewale Abimbola O.; Maislin Greg; Skeie Svein; Lavizzo-Mourey Risa J.; Rubin Harvey (The Gerontological Society of America, 1995-09-01)
    Background. Acute gastroenteritis is a cause of considerable morbidity and mortality in the elderly population. A prospective assessment of acute diarrhea in three community-based long-stay homes is described. Methods. A ...
  • Eekelen J. Anke M. Van; OitzlE Melly S.; De Kloet Ronald (The Gerontological Society of America, 1995-03-01)
    This study was designed to examine adrenocortical function in old (30 months) and young (6 months) male Brown Norway rats. The following observations were made. First, stress induced a higher pituitary adrenocorticotropic ...
  • Robbins Jo Anne; Levine Ross; Wood Jennifer; Roecker Ellen B.; Luschei Erich (The Gerontological Society of America, 1995-09-01)
    Background. Tongue activity plays a crucial role in both oral and pharyngeal phases of swallowing. In this study, maximum lingual isometric and swallowing pressures were quantified in two groups of healthy men to investigate ...
  • Quoniam Cynthia; Hay Laurette; Roll Jean-Pierre; Harlay Franchise (The Gerontological Society of America, 1995-05-01)
    The effects of aging on two sensorimotor levels of propriomuscular function were investigated in a young (20- to 44- year-old) and an elderly (60- to 86-year-old) population by eliciting segmental reflex and postural ...
  • Evans William J.; Hurley Ben F. (The Gerontological Society of America, 1995-11-01)
    Muscular strength can be measured by cable tensiometry, non-motorized dynamometry (e.g., handgrip dynamometer), motorized dynamometry, or with free weights or exercise machines. Advantages and disadvantages of each are ...
  • Ohtsuka Hiroaki; Takahashi Ryoya; Goto Sataro (The Gerontological Society of America, 1995-09-01)
    It has been demonstrated that the amount of ubiquitin (Ub)-protein conjugates increases in the whole brain homogenates of old mice. To determine the specificity of the accumulation of the conjugates, we further investigated ...
  • Snyder David L.; Johnson Mark D.; Aloyo Vince; Eskin Bernard; Roberts Jay (The Gerontological Society of America, 1995-11-01)
    The purpose of this study was to determine if the age-related decrease in norepinephrine (NE) release from cardiac adrenergic nerve terminals is due to a defect in Ca2+ movement into the nerve terminal or to an alteration ...
  • Barber B.J.; Babbitt Ruth A.; Parameswaran Sandhya; Dutta Sandeep (The Gerontological Society of America, 1995-09-01)
    Measurements of effects of age-related changes on loose connective tissue protein concentrations and water are lacking. Tissue hydration is an important determinant of tissue protein diffusion coefficients and hydraulic ...
  • Mudumbi Ramagopal V.; Olson Richard D.; Hubler Bruce E.; Montamat Stephen C.; Vestal Robert E. (The Gerontological Society of America, 1995-11-01)
    Interventions known to increase cytoplasmic Ca2+ appear to amplify age-related impairment of cardiac function. In addition, increased release of interstitial adenosine, an endogenous nucleoside, has been suggested to mediate ...
  • Masuda Makihiko; Nukuzuma Chiyoko; Kazusaka Akio; Fujita Shoichi (The Gerontological Society of America, 1995-09-01)
    Age-associated alterations in activation and deactivation of benzo[a]pyrene (BP), furylfuramide (AF2), and 2- nitrofluorene (NF) in rat liver were investigated. A modified Ames mutagenicity test system used liver 9000 g ...
  • Waters Stephen M.; Davis Thomas P. (The Gerontological Society of America, 1995-09-01)
    The levels of specific neuropeptides and the activity of neuropeptidases known to degrade neuropeptides have been shown to be altered in senile dementia of the Alzheimer's type (SDAT) postmortem brain. We examined the ...