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Автор RUIZ, A. DIEZ
Автор PEREZ, J. L. SANTOS
Автор MARTINEZ, G. LOPEZ
Автор CALVÍN, J.
Автор EXTREMERA, B. GIL
Автор GEA, F GUTIERREZ
Дата выпуска 1993
dc.description The existence of a cellular immune deficit in alcoholic cirrhosis, and the alterations described in cytokine synthesis in this disease, led us to compare serum concentrations of tumour necrosis factor-α, interleukin-1β and interleukin-6 in a group of 33 patients with alcoholic cirrhosis (classified according to the Child-Pugh grade of severity of liver disease) and 43 healthy volunteers. Serum concentrations of tumour necrosis factor-α, interleukin-1β and interleukin-6 were significantly raised in alcoholic cirrhosis patients, with no significant differences between patients with liver disease of different grades of severity. The results suggest that cirrhosis involves the activation of the monocyte-macrophage system, which may contribute to the progression of the disease and its clinical manifestations.
Формат application.pdf
Издатель Oxford University Press
Копирайт © 1993 Medical Council on Alcoholism
Тема Articles
Название TUMOUR NECROSIS FACTOR, INTERLEUKIN-1 AND INTERLEUKIN-6 IN ALCOHOLIC CIRRHOSIS
Тип research-article
Electronic ISSN 1464-3502
Print ISSN 0735-0414
Журнал Alcohol and Alcoholism
Том 28
Первая страница 319
Последняя страница 323
Аффилиация Department of Medicine, School of Medicine, University of GranadaE-18071 Granada, Spain
Выпуск 3

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