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Автор SULLIVAN, J. S.
Автор DENBOROUGH, M. A.
Дата выпуска 1981
dc.description Contractures induced by halothane, caffeine, suxamethonium chloride and potassium chloride in malignant hyperpyrexia-susceptible (MHS) and control swine skeletal muscle preparations were temperature-dependent, but differed in their temperature response profiles. Increasing the temperatures from 20 °C to 37 °C increased drug-induced contractures in MHS muscle. At 5 °C drug-induced contractures were not inhibited by dantrolene sodium, deuterium oxide or glycerination in either MHS or control muscle. These observations give further support to the view that the abnormality in MHS skeletal muscle is associated with the mechanism of excitation-contraction coupling.
Формат application.pdf
Издатель Oxford University Press
Копирайт © Macmillan Publishers Ltd
Тема EXPERIMENTAL
Название TEMPERATURE DEPENDENCE OF MUSCLE FUNCTION IN MALIGNANT HYPERPYREXIA-SUSCEPTIBLE SWINE
Тип research-article
Electronic ISSN 1471-6771
Print ISSN 0007-0912
Журнал BJA: British Journal of Anaesthesia
Том 53
Первая страница 1217
Последняя страница 1222
Аффилиация Department of Clinical Science, John Curtin School of Medical Research, The Australian National UniversityCanberra, A.C.T., Australia
Выпуск 11

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