Автор |
SULLIVAN, J. S. |
Автор |
DENBOROUGH, M. A. |
Дата выпуска |
1981 |
dc.description |
Contractures induced by halothane, caffeine, suxamethonium chloride and potassium chloride in malignant hyperpyrexia-susceptible (MHS) and control swine skeletal muscle preparations were temperature-dependent, but differed in their temperature response profiles. Increasing the temperatures from 20 °C to 37 °C increased drug-induced contractures in MHS muscle. At 5 °C drug-induced contractures were not inhibited by dantrolene sodium, deuterium oxide or glycerination in either MHS or control muscle. These observations give further support to the view that the abnormality in MHS skeletal muscle is associated with the mechanism of excitation-contraction coupling. |
Формат |
application.pdf |
Издатель |
Oxford University Press |
Копирайт |
© Macmillan Publishers Ltd |
Тема |
EXPERIMENTAL |
Название |
TEMPERATURE DEPENDENCE OF MUSCLE FUNCTION IN MALIGNANT HYPERPYREXIA-SUSCEPTIBLE SWINE |
Тип |
research-article |
Electronic ISSN |
1471-6771 |
Print ISSN |
0007-0912 |
Журнал |
BJA: British Journal of Anaesthesia |
Том |
53 |
Первая страница |
1217 |
Последняя страница |
1222 |
Аффилиация |
Department of Clinical Science, John Curtin School of Medical Research, The Australian National UniversityCanberra, A.C.T., Australia |
Выпуск |
11 |