| Автор | Daniel, Philip B. |
| Автор | Walker, William H. |
| Автор | Habener, Joel F. |
| Дата выпуска | 1998 |
| dc.description | ▪ Abstract Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger produced in cells in response to hormones and nutrients. The production of cAMP is dependent upon the actions of many different proteins that affect its synthesis and degradation. An important function of cAMP is to activate the phosphorylating enzyme, protein kinase A. The key roles of cAMP and protein kinase A in the phosphorylation and regulation of enzyme substrates involved in intermediary metabolism are well known. A newly discovered role for protein kinase A is in the phosphorylation and activation of transcription factors that are critical for the control of the transcription of genes in response to elevated levels of cAMP. |
| Формат | application.pdf |
| Издатель | Annual Reviews |
| Копирайт | Annual Reviews |
| Название | CYCLIC AMP SIGNALING AND GENE REGULATION |
| DOI | 10.1146/annurev.nutr.18.1.353 |
| Print ISSN | 0199-9885 |
| Журнал | Annual Review of Nutrition |
| Том | 18 |
| Первая страница | 353 |
| Последняя страница | 383 |
| Аффилиация | Daniel, Philip B.; Laboratory of Molecular Endocrinology, Massachusetts General Hospital, and Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02114; e-mail: habenerj@a1.mgh.harvard.edu |
