Chelation-control in nucleophilic addition to Cr(CO)3-complexed aryl aldehydes
Kumar Tipparaju, Suresh; Puranik, Vedavati G.; Sarkar, Amitabha; Kumar Tipparaju Suresh; Division of Organic Chemistry (Synthesis), National Chemical Laboratory; Puranik Vedavati G.; Physical Chemistry Division, National Chemical Laboratory; Sarkar Amitabha; Division of Organic Chemistry (Synthesis), National Chemical Laboratory
Журнал:
Organic & Biomolecular Chemistry
Дата:
2003
Аннотация:
One or more methoxy groups on the benzylic carbon at the ortho-position of tricarbonylchromium-complexed aryl aldehydes (2, 3 or 4) permit chelation-controlled addition of nucleophiles to the carbonyl function in the presence of Lewis acids. In the absence of a Lewis acid additive, a complementary set of diastereomeric products are obtained.
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