A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS
Powers, Michael A.; Koev, Stephan T.; Schleunitz, Arne; Yi, Hyunmin; Hodzic, Vildana; Bentley, William E.; Payne, Gregory F.; Rubloff, Gary W.; Ghodssi, Reza; Powers Michael A.; Department of Electrical and Computer Engineering; Institute for Systems Research (ISR); Koev Stephan T.; Department of Electrical and Computer Engineering; Institute for Systems Research (ISR); Schleunitz Arne; Department of Electrical and Computer Engineering; Institute for Systems Research (ISR); Yi Hyunmin; University of Maryland Biotechnology Institute (UMBI); Hodzic Vildana; Department of Electrical and Computer Engineering; Bentley William E.; Department of Chemical Engineering; University of Maryland Biotechnology Institute (UMBI); Bioengineering Program, University of Maryland; Payne Gregory F.; University of Maryland Biotechnology Institute (UMBI); Bioengineering Program, University of Maryland; Rubloff Gary W.; Department of Materials Science and Engineering; Institute for Systems Research (ISR); Bioengineering Program, University of Maryland; Ghodssi Reza; Department of Electrical and Computer Engineering; Institute for Systems Research (ISR); Bioengineering Program, University of Maryland
Журнал:
Lab on a Chip
Дата:
2005
Аннотация:
We report a new approach for microfluidic optical bioanalysis that is based on the electrically driven assembly of bio-components on a transparent sidewall and the optical detection of the assembled components using planar waveguides. This allows localized electrical signals for bio-assembly and optical signals for bio-detection that can easily be applied in MEMS systems. We demonstrate a BioMEMS design incorporating this scheme and its output signal when using fluorescent detection.
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