Synthesis and antibody binding properties of glycodendrimers bearing the tumor related T-antigen
Baek, Myung-Gi; Rittenhouse-Olson, Kate; Roy, René; Baek Myung-Gi; Department of Chemistry, University of Ottawa; Rittenhouse-Olson Kate; Department of Microbiology and Immunology, Roswell Park Division, State University of New York at Buffalo; Roy René; Department of Chemistry, University of Ottawa
Журнал:
Chemical Communications
Дата:
2001
Аннотация:
Breast cancer marker T-antigen (Gal(β1-3)αGalNAc) was prepared as an allyl glycoside that was transformed into an active ester and coupled to a series of poly(amidoamine) dendrimers showing strong binding to mouse monoclonal IgG antibodies and serving as useful coating antigens in microtiter plates.
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