We consider an open string described by an action of the Dirac-Nambu-Goto type with topological corrections which affect the boundary conditions but not the equations of motion. The most general addition of this kind is a sum of the Gauss-Bonnet action and the first Chern number (when the background spacetime dimension is four) of the normal bundle to the string world-sheet. We examine the modification introduced by such terms in the boundary conditions at the ends of the string.