Modeling molecular motors as folding-unfolding cycles
A. Hansen; M. H. Jensen; K. Sneppen; G. Zocchi; A. Hansen; Niels Bohr Institute and NORDITA - Blegdamsvej 17, DK-2100 Ø, Denmark; M. H. Jensen; Niels Bohr Institute and NORDITA - Blegdamsvej 17, DK-2100 Ø, Denmark; K. Sneppen; Niels Bohr Institute and NORDITA - Blegdamsvej 17, DK-2100 Ø, Denmark; G. Zocchi; Niels Bohr Institute and NORDITA - Blegdamsvej 17, DK-2100 Ø, Denmark
Журнал:
EPL (Europhysics Letters)
Дата:
2000-04-01
Аннотация:
We propose a model for motor proteins based on a hierarchical Hamiltonian that we have previously introduced to describe protein folding. The proposed motor model has a power stroke of high efficiency and an overall dynamics that is consistent with a linear load-velocity response. The model suggests a connection between folding and function of allosteric proteins.
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