| Автор | Keith Boddy |
| Автор | George Will |
| Автор | Barbara M Holmes |
| Дата выпуска | 1969-07-01 |
| dc.description | <sup>57</sup>Co-labelled vitamin B<sub>12</sub> (0.25 µg; 0.25 µCi) has been used in a double tracer test of absorption, together with <sup>58</sup>Co-labelled vitamin B12 (0.4 µg; 0.4 µCi), using a whole-body monitor. It was found that variation of the counting-rate on the day of administration was small and was similar for both isotopes. The fraction of <sup>58</sup>Co γ-rays detected in the <sup>57</sup>Co energy band also showed little variation and the patient was able to act as his own phantom. The range of absorption of vitamin B<sub>12</sub> was 21.3-63.3% in control subjects and 1.8-11.8% in patients with pernicious anaemia. The absorption of vitamin B<sub>12</sub> with intrinsic factor, determined simultaneously, was always at least twice the absorption of vitamin B<sub>12</sub> alone in patients with pernicious anaemia and always less than twice in control subjects. The results demonstrate the suitability of <sup>57</sup>Co-labelled vitamin B<sub>12</sub> in whole-body monitoring studies of vitamin B<sub>12</sub> metabolism. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Название | An evaluation of <sup>57</sup>Co-labelled vitamin B<sub>12</sub> in a double tracer test of absorption using a whole-body monitor |
| Тип | paper |
| DOI | 10.1088/0031-9155/14/3/307 |
| Electronic ISSN | 1361-6560 |
| Print ISSN | 0031-9155 |
| Журнал | Physics in Medicine and Biology |
| Том | 14 |
| Первая страница | 455 |
| Последняя страница | 462 |
| Аффилиация | Keith Boddy; Scottish (Universities) Research Reactor Centre, East Kilbride, Glasgow, and Gateside Hospital, Greenock, UK |
| Аффилиация | George Will; Scottish (Universities) Research Reactor Centre, East Kilbride, Glasgow, and Gateside Hospital, Greenock, UK |
| Аффилиация | Barbara M Holmes; Scottish (Universities) Research Reactor Centre, East Kilbride, Glasgow, and Gateside Hospital, Greenock, UK |
| Выпуск | 3 |
