| Автор | A Morgan |
| Автор | A Holmes |
| Автор | F W Pratley |
| Дата выпуска | 1990-06-01 |
| dc.description | The solubility of actinides, associated with contaminated estuarine silt from West Cumbria, was measured in the rat lung. This material is similar mineralogically to airborne particles of silt involved in the sea-to-land transfer of radioactivity. A total of 25 mg of silt was administered to rats by multiple intratracheal instillations over a period of 7 weeks. There was no evidence of the rapid lung clearance phase normally observed in the rat and, after an initial period of stasis, most of the plutonium and americium was cleared from the lung with a half time of approximately 240 days. Some 15% of the retained plutonium isotopes and 10% of the <sup>241</sup>Am were transferred to the skeleton over a period of about 3 months, indicating that both behave as ICRP Class W materials. Uptake by the liver was about 2% for both Pu and Am. Levels of actinides in the lung-associated lymph nodes were either at or blow the minimum level of detection. The significance of these results in relation to the ICRP lung model and to generalised derived limits for plutonium is discussed. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Название | Solubility in the rat lung of actinides associated with estuarine silt from West Cumbria |
| Тип | paper |
| DOI | 10.1088/0952-4746/10/2/007 |
| Electronic ISSN | 1361-6498 |
| Print ISSN | 0952-4746 |
| Журнал | Journal of Radiological Protection |
| Том | 10 |
| Первая страница | 135 |
| Последняя страница | 142 |
| Аффилиация | A Morgan; Environmental Medical Sciences Div., Harwell Lab., Didcot, UK |
| Аффилиация | A Holmes; Environmental Medical Sciences Div., Harwell Lab., Didcot, UK |
| Аффилиация | F W Pratley; Environmental Medical Sciences Div., Harwell Lab., Didcot, UK |
| Выпуск | 2 |
