During magnetoresistance measurement of Bi-2212 single crystals, we found the resistance in the c-axis direction exhibited a huge magnetic enhancement (H perpendicular to the a-b-plane) while the onset transition temperature along the c-axis showed a large depression when the magnetic fields were over a certain value (H >180 Oe). No such phenomena were observed in small applied magnetic fields and in a-b-plane magnetoresistance measurements. By changing different probes (eight probes being attached to the sample, each side having four probes) for the measurement of the magnetoresistance along the c-axis with H = 2000 Oe, we found that the resistance along the c-axis in the temperature region was only related to the measuring dimensions and onset remained unchanged. Our results provided evidence that both Lorentz-force-independent fluctuation-induced dissipation and Lorentz-force-dependent vortex motion dissipation exist in the mixed state.