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Автор S Bignall
Автор R I Kitney
Автор D Summers
Дата выпуска 1993-11-01
dc.description In order to define the complex interactions between external stimuli and nonlinear physiological systems, a technique (the frequency-tracking locus, FTL) was devised that describes the cycle-by-cycle changes in phase angle and amplitude between 2 signals. Qualitative assessment of the nature of interactions between the signals can be made by examining the FTL Quantitation of the extent of entrainment of the spontaneous physiological rhythm is possible after deriving a numerical index (the path-length index, PLI) describing the departure of the system from a fully entrained state. The FTL was applied to the study of interactions between spontaneous respiratory effort and mechanical inflation in preterm newborn babies undergoing mechanical ventilation. Stable and unstable states of 1:1 interaction were noted while integer-ratio relationships were seen at low rates of mechanical ventilation. Stable states of entrainment corresponded to a PLI value near unity, and the value of PLI increased rapidly as interaction became unstable. The FTL may be used to describe complex interactions in physiological systems, and may be used as a guide to baby-ventilator matching during mechanical ventilation of the newborn.
Формат application.pdf
Издатель Institute of Physics Publishing
Название Use of the frequency-tracking locus in estimating the degree of respiratory entrainment in preterm infants
Тип paper
DOI 10.1088/0967-3334/14/4/005
Electronic ISSN 1361-6579
Print ISSN 0967-3334
Журнал Physiological Measurement
Том 14
Первая страница 441
Последняя страница 454
Аффилиация S Bignall; Dept. of Peadiatrics, St. Mary's Hospital, London, UK
Аффилиация R I Kitney; Dept. of Peadiatrics, St. Mary's Hospital, London, UK
Аффилиация D Summers; Dept. of Peadiatrics, St. Mary's Hospital, London, UK
Выпуск 4

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