| Автор | Davis, Karen L |
| Автор | Martin, Emil |
| Автор | Turko, Illarion V |
| Автор | Murad, Ferid |
| Дата выпуска | 2001 |
| dc.description | ▪ Abstract Nitric oxide (NO), a simple free radical gas, elicits a surprisingly wide range of physiological and pathophysiological effects. NO interacts with soluble guanylate cyclase to evoke many of these effects. However, NO can also interact with molecular oxygen and superoxide radicals to produce reactive nitrogen species that can modify a number of macromolecules including proteins, lipids, and nucleic acids. NO can also interact directly with transition metals. Here, we have reviewed the non–3′,5′-cyclic-guanosine-monophosphate–mediated effects of NO including modifications of proteins, lipids, and nucleic acids. |
| Формат | application.pdf |
| Издатель | Annual Reviews |
| Копирайт | Annual Reviews |
| Название | NOVEL EFFECTS OF NITRIC OXIDE |
| DOI | 10.1146/annurev.pharmtox.41.1.203 |
| Print ISSN | 0362-1642 |
| Журнал | Annual Review of Pharmacology and Toxicology |
| Том | 41 |
| Первая страница | 203 |
| Последняя страница | 236 |
| Аффилиация | Davis, Karen L; Department of Integrated Biology and Pharmacology and Institute for Molecular Medicine, University of Texas Houston Health Science Center, Houston, Texas 77030; e-mail: karen.l.davis@uth.tmc.edu , emil.martin@uth.tmc.edu , illarion.v.turko@uth.tmc.edu , ferid.murad@uth.tmc.edu |
