| Автор | Wall, Michael E. |
| Автор | Gallagher, Stephen C. |
| Автор | Trewhella, Jill |
| Дата выпуска | 2000 |
| dc.description | ▪ Abstract Proteins and RNA undergo intricate motions as they carry out functions in biological systems. These motions frequently entail large-scale conformational changes that induce changes in the surface structure, or shape, of a molecule. This review describes the experimental characterization of large-scale shape changes in proteins and macromolecular complexes and the effects of such changes on macromolecular behavior. We describe several important results that have been obtained by using small-angle scattering, which is emerging as a powerful technique for determining macromolecular shapes and elucidating the quaternary structure of macromolecular assemblies. |
| Формат | application.pdf |
| Издатель | Annual Reviews |
| Копирайт | Annual Reviews |
| Название | LARGE-SCALE SHAPE CHANGES IN PROTEINS AND MACROMOLECULAR COMPLEXES |
| DOI | 10.1146/annurev.physchem.51.1.355 |
| Print ISSN | 0066-426X |
| Журнал | Annual Review of Physical Chemistry |
| Том | 51 |
| Первая страница | 355 |
| Последняя страница | 380 |
| Аффилиация | Wall, Michael E.; Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545; e-mail: mewall@lanl.gov gallagher@lanl.gov jtrewhella@lanl.gov |
