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Автор Steve Arscott
Автор Séverine Le Gac
Автор Christian Druon
Автор Pierre Tabourier
Автор Christian Rolando
Дата выпуска 2004-02-01
dc.description We present a novel nanoelectrospray emitter tip based on the principle of a nib rather than a nozzle for nano-electrospray ionization–mass spectrometry (ESI–MS) applications. The fabrication of the micro-nibs relies on micromachining techniques using the epoxy-based negative photoresist SU-8. A double exposure photolithographic process has been employed to form a nib in a membrane-like structure. The nibs contained a capillary slot measuring 20 µm at the tip end. The nib sources were successfully tested on an ion trap mass spectrometer using standard peptide samples at low concentrations, down to 1 µM. High voltage (HV) supply was achieved using platinum wire inserted in a liquid reservoir. A Taylor cone was clearly seen protruding from the nib tip and was determined by the dimensions of the capillary slot.
Формат application.pdf
Издатель Institute of Physics Publishing
Копирайт 2004 IOP Publishing Ltd
Название A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications
Тип paper
DOI 10.1088/0960-1317/14/2/021
Electronic ISSN 1361-6439
Print ISSN 0960-1317
Журнал Journal of Micromechanics and Microengineering
Том 14
Первая страница 310
Последняя страница 316
Выпуск 2

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