Автор | Steve Arscott |
Автор | Séverine Le Gac |
Автор | Christian Druon |
Автор | Pierre Tabourier |
Автор | Christian Rolando |
Дата выпуска | 2004-02-01 |
dc.description | We present a novel nanoelectrospray emitter tip based on the principle of a nib rather than a nozzle for nano-electrospray ionization–mass spectrometry (ESI–MS) applications. The fabrication of the micro-nibs relies on micromachining techniques using the epoxy-based negative photoresist SU-8. A double exposure photolithographic process has been employed to form a nib in a membrane-like structure. The nibs contained a capillary slot measuring 20 µm at the tip end. The nib sources were successfully tested on an ion trap mass spectrometer using standard peptide samples at low concentrations, down to 1 µM. High voltage (HV) supply was achieved using platinum wire inserted in a liquid reservoir. A Taylor cone was clearly seen protruding from the nib tip and was determined by the dimensions of the capillary slot. |
Формат | application.pdf |
Издатель | Institute of Physics Publishing |
Копирайт | 2004 IOP Publishing Ltd |
Название | A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications |
Тип | paper |
DOI | 10.1088/0960-1317/14/2/021 |
Electronic ISSN | 1361-6439 |
Print ISSN | 0960-1317 |
Журнал | Journal of Micromechanics and Microengineering |
Том | 14 |
Первая страница | 310 |
Последняя страница | 316 |
Выпуск | 2 |