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Автор Hong, Chien-Chong
Автор Choi, Jin-Woo
Автор Ahn, Chong H
Дата выпуска 2007-02-01
dc.description A new fluidic delivery system for driving fluids on disposable lab-on-a-chip systems using an air-bursting detonator device has been designed, fabricated and successfully characterized in this paper for driving fluid on disposable lab-on-a-chip or point-of-care testing. The disposable air-bursting detonator device uses a pressurized gas source, sealed in a microcavity with a thermoplastic membrane. A microheater positioned on the thermoplastic membrane is used as an electro-thermal heater to melt the sealing membrane thus releasing the pressurized gas to the integrated microfluidic system. The pressurized gas drives liquid samples through designated microfluidic channels. Both air pressure and detonating temperature are adjustable to get the desired driving pressure responses. A 40 mW electrical power pulse applied to the microheater for 700 ms resulted in releasing 650 µJ of stored pneumatic energy in the microcavity and driving a 500 nl sample through the microchannels of an integrated test system. The dynamic pressure response of the fabricated air-bursting detonator has been fully simulated and characterized. Due to its compact structure and fast response, the air-bursting detonator device will be a promising alternative power source to drive fluid samples in disposable lab-on-a-chip systems or portable clinical diagnostic kits.
Формат application.pdf
Издатель Institute of Physics Publishing
Копирайт 2007 IOP Publishing Ltd
Название An on-chip air-bursting detonator for driving fluids on disposable lab-on-a-chip systems
Тип paper
DOI 10.1088/0960-1317/17/2/029
Electronic ISSN 1361-6439
Print ISSN 0960-1317
Журнал Journal of Micromechanics and Microengineering
Том 17
Первая страница 410
Последняя страница 417
Последняя страница 417
Аффилиация Hong, Chien-Chong; MicroSystems and BioMEMS Lab., Department of Electrical and Computer Engineering and Computer Science, University of Cincinnati, PO Box 210030, Cincinnati, OH 45221-0030, USA
Аффилиация Choi, Jin-Woo; MicroSystems and BioMEMS Lab., Department of Electrical and Computer Engineering and Computer Science, University of Cincinnati, PO Box 210030, Cincinnati, OH 45221-0030, USA
Аффилиация Ahn, Chong H; MicroSystems and BioMEMS Lab., Department of Electrical and Computer Engineering and Computer Science, University of Cincinnati, PO Box 210030, Cincinnati, OH 45221-0030, USA
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