The paper is devoted to the theoretical investigation of the circular dichroism (CD) and optical rotatory dispersion (ORD) spectra of turbid layers with large particles of arbitrary shapes. The cases of oriented cylinders and spheroids are considered in detail. It is assumed that the optical thickness of layers is low and the refractive index of scatterers is close to the refractive index of a host medium, which is usually the case for bio-liquids. It is found that the simple correction function allows to transform CD and ORD spectra measured for turbid layers to that of particles. This result could be of importance for studies of living cells molecular structure changes during their life cycles.