Автор |
Capri, Miriam |
Автор |
Mesirca, Pietro |
Автор |
Remondini, Daniel |
Автор |
Carosella, Simona |
Автор |
Pasi, Sara |
Автор |
Castellani, Gastone |
Автор |
Franceschi, Claudio |
Автор |
Bersani, Ferdinando |
Дата выпуска |
2004-12-01 |
dc.description |
In the last 30 years, an increasing public concern about the possible harmful effects of electromagnetic fields generated by power lines and domestic appliances has pushed the scientific community to search for a correct and comprehensive answer to this problem. In this work the effects of exposure to 50 Hz sinusoidal magnetic fields, with a magnetic flux density of 0.05 mT and 2.5 mT (peak values), were studied on human peripheral blood mononuclear cells (PBMCs) collected from healthy young and elderly donors. Cell activation and proliferation were investigated by using flow cytometry techniques and <sup>3</sup>H-TdR incorporation assays, respectively. The results obtained indicated that exposure to the fields altered neither DNA synthesis nor the capacity of lymphocytes to enter the activation phase and progress into the cell cycle. Thus, the conclusions are that two important functional phases of human lymphocytes, such as activation and proliferation, are not affected by exposures to 50 Hz magnetic fields similar to those found under power lines. |
Формат |
application.pdf |
Издатель |
Institute of Physics Publishing |
Копирайт |
2004 IOP Publishing Ltd |
Название |
50 Hz sinusoidal magnetic fields do not affect human lymphocyte activation and proliferation in vitro |
Тип |
paper |
DOI |
10.1088/1478-3967/1/4/003 |
Electronic ISSN |
1478-3975 |
Print ISSN |
1478-3967 |
Журнал |
Physical Biology |
Том |
1 |
Первая страница |
211 |
Последняя страница |
219 |
Аффилиация |
Capri, Miriam; Department of Experimental Pathology, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Аффилиация |
Mesirca, Pietro; ICEmB at Department of Physics, Via Berti Pichat 6/2, University of Bologna, 40127 Bologna, Italy; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Аффилиация |
Remondini, Daniel; ICEmB at Department of Physics, Via Berti Pichat 6/2, University of Bologna, 40127 Bologna, Italy; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Аффилиация |
Carosella, Simona; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Аффилиация |
Pasi, Sara; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Аффилиация |
Castellani, Gastone; ICEmB at Department of Physics, Via Berti Pichat 6/2, University of Bologna, 40127 Bologna, Italy; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Аффилиация |
Franceschi, Claudio; Department of Experimental Pathology, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy; Scientific Director of INRCA, Institute of National Research on Ageing, Department of Gerontology, Via Birarelli 9, 60100 Ancona, Italy; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Аффилиация |
Bersani, Ferdinando; ICEmB at Department of Physics, Via Berti Pichat 6/2, University of Bologna, 40127 Bologna, Italy; CIG: Centro Interdipartimentale ‘L. Galvani’, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy |
Выпуск |
4 |