| Автор | Kitamura, Toyoyuki |
| Автор | Peyrard, Michel |
| Автор | Cuesta Lopez, Santiago |
| Дата выпуска | 2005-09-01 |
| dc.description | The theory of the liquid–glass transition is extended to describe the polymerization of RNA in a nucleotide-condensed state. In the glassy state the ribose subunits are joined by a 2′–5′ or 3′–5′ phosphodiester linkage to form the ribose–phosphate backbone similar to oligosaccharides and polysaccharides. The occurrence of the glass transition requires two conditions: (1) a supercooled state in a nucleotide-condensed state should exist below the temperature at which the whole RNA hydrolyzes; (2) the Gibbs free energy due to the Kauzmann entropy, which obeys a Curie law with a negative sign, must be larger than the height of the potential barrier for nucleotides to overcome to form the binding. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Копирайт | 2005 IOP Publishing Ltd |
| Название | A model on the origin of RNA |
| Тип | paper |
| DOI | 10.1088/1478-3975/2/3/007 |
| Electronic ISSN | 1478-3975 |
| Print ISSN | 1478-3967 |
| Журнал | Physical Biology |
| Том | 2 |
| Первая страница | 200 |
| Последняя страница | 206 |
| Аффилиация | Kitamura, Toyoyuki; Ecole Normale Supérieure de Lyon, 46, Allée d'Italie, 69364 Lyon Cedex 07, France; Nagasaki Institute of Applied Science, Nagasaki 851-0193, Japan |
| Аффилиация | Peyrard, Michel; Ecole Normale Supérieure de Lyon, 46, Allée d'Italie, 69364 Lyon Cedex 07, France |
| Аффилиация | Cuesta Lopez, Santiago; Ecole Normale Supérieure de Lyon, 46, Allée d'Italie, 69364 Lyon Cedex 07, France; University of Zaragoza, Pedro Cerbuna s/n 50.009 Zaragoza, Spain |
| Выпуск | 3 |
