| Автор | Banik, Suman K |
| Автор | Fenley, Andrew T |
| Автор | Kulkarni, Rahul V |
| Дата выпуска | 2009-12-01 |
| dc.description | We present a framework for analyzing luminescence regulation during quorum sensing in the bioluminescent bacterium Vibrio harveyi. Using a simplified model for signal transduction in the quorum sensing pathway, we identify key dimensionless parameters that control the system's response. These parameters are estimated using experimental data on luminescence phenotypes for different mutant strains. The corresponding model predictions are consistent with results from other experiments which did not serve as input for determining model parameters. Furthermore, the proposed framework leads to novel testable predictions for luminescence phenotypes and for responses of the network to different perturbations. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Копирайт | 2009 IOP Publishing Ltd |
| Название | A model for signal transduction during quorum sensing in Vibrio harveyi |
| Тип | paper |
| DOI | 10.1088/1478-3975/6/4/046008 |
| Electronic ISSN | 1478-3975 |
| Print ISSN | 1478-3967 |
| Журнал | Physical Biology |
| Том | 6 |
| Первая страница | 46008 |
| Последняя страница | 46017 |
| Аффилиация | Banik, Suman K; |
| Аффилиация | Kulkarni, Rahul V; |
| Аффилиация | Fenley, Andrew T; Department of Physics, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0435, USA |
| Выпуск | 4 |
