We have designed combined passive and active thermal control system to achieve sub microkelvin temperature stability and uniformity over an optics bench size enclosure, which has an analogous structure to the LISA spacecraft. For the passive control, we have constructed a new thermal enclosure that has a multilayer structure with alternative conducting and insulating layers, which enables the temperature uniformity and ease the burden of the active control. The thermal enclosure becomes an important test facility for Modular Gravitational Reference Sensor (MGRS) development. For the active control, we have developed a model predictive control (MPC) algorithm, which will regulate temperature variations of the proof-mass (PM) down to sub-microkelvin over the LISA science band. The LISA mission requires extremely tight temperature control, which is as low as 30 μK/ over 0.1 mHz to 1 Hz. Both temporal stability and spatial uniformity in temperature must be achieved. Optical path length variations on optical bench must be kept below 40 pm/ over 0.1 mHz to 1 Hz. Temperature gradient across the proof mass housing also must be controlled to reduce differential thermal pressure. Thermal disturbances due to, for example, solar radiation and heat generation from electronics, are expected to be significant disturbance source to the LISA sensitivity requirements. The MGRS will alleviate the thermal requirement due to its wider gap between the proof-mass and the housing wall. However, a thermally stable and uniform environment is highly desirable to achieve more precise science measurement for future space science missions.