| Автор | Chu, Viet Ha |
| Автор | Nghiem, Thi Ha Lien |
| Автор | La, Thi Huyen |
| Автор | Ung, Thi Dieu Thuy |
| Автор | Le, Quang Huan |
| Автор | Tong, Kim Thuan |
| Автор | Nguyen, Quang Liem |
| Автор | Tran, Hong Nhung |
| Дата выпуска | 2010-06-01 |
| dc.description | This work presents the results of the attachment of Qdot 655 ITK<sup>TM</sup> amino (PEG) quantum dots (QDs) (Invitrogen) and CdTe QDs (provided by Institute of Materials Science, VAST) to HER2 (Human Epidermal growth factor Receptor 2) specific phage antibodies (Abs) (provided by Institute of Biotechnology, VAST) in solution. The QDs were attached to the phage display specific HER2 Abs to form a complex QD–Ab. The QDs and complex QD–Ab were characterized by UV-VIS spectroscopy, transmission electron microscopy (TEM) and fluorescence microscopy. The fluorescence images show the QDs conjugated to the phage. Due to the QDs attaching to the surface, the phage dimensions were amplified, so its shape could be observed by optical microscopy. The complex QD–Ab was stable and lasted for a month. The results illustrate the value of the HER2 phage–QD complex as a cancer detection platform. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Копирайт | 2010 Vietnam Academy of Science & Technology |
| Название | Attaching quantum dots to HER2 specific phage antibodies |
| Тип | paper |
| DOI | 10.1088/2043-6254/1/2/025005 |
| Electronic ISSN | 2043-6262 |
| Print ISSN | 2043-6254 |
| Журнал | Advances in Natural Sciences: Nanoscience and Nanotechnology |
| Том | 1 |
| Первая страница | 25005 |
| Последняя страница | 25008 |
| Аффилиация | Chu, Viet Ha; Institute of Physics, Vietnam Academic of Science and Technology (VAST), 10 Dao Tan, Hanoi, Vietnam |
| Аффилиация | Nghiem, Thi Ha Lien; Institute of Physics, Vietnam Academic of Science and Technology (VAST), 10 Dao Tan, Hanoi, Vietnam |
| Аффилиация | La, Thi Huyen; Institute of Biotechnology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam |
| Аффилиация | Ung, Thi Dieu Thuy; Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam |
| Аффилиация | Le, Quang Huan; Institute of Biotechnology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam |
| Аффилиация | Tong, Kim Thuan; Institute of Biotechnology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam |
| Аффилиация | Nguyen, Quang Liem; Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam |
| Аффилиация | Tran, Hong Nhung; Institute of Physics, Vietnam Academic of Science and Technology (VAST), 10 Dao Tan, Hanoi, Vietnam |
| Выпуск | 2 |
