| Автор | Zhang, Qi Dong |
| Автор | Piro, Benoît |
| Автор | Noël, Vincent |
| Автор | Reisberg, Steeve |
| Автор | Pham, Minh-Chau |
| Дата выпуска | 2010-12-01 |
| dc.description | In this paper, we first review different strategies reported in the literature to elaborate electrochemical DNA sensors based on carbon nanotubes. Then we report a new strategy to graft both redox and DNA probes onto carbon nanotubes to make a label-free DNA sensor. Oxidized single-walled carbon nanotubes are first immobilized on a self-assembled monolayer of cysteamine. Then a redox probe, a quinone derivative 3-[(2-aminoethyl) sulfanyl-5-hydroxy-1,4-naphthoquinone], is grafted onto the free carboxylic groups of the nanotubes. After that, for DNA probe grafting, new carboxylic sites are generated via an aryl diazonium route. After hybridization with a complementary sequence, the conformational changes of DNA could influence the redox kinetics of quinone, leading to a current increase in the redox signal, detected by square wave voltammetry. The system is selective, as it can distinguish a single mismatched sequence from the complementary one. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Копирайт | 2010 Vietnam Academy of Science & Technology |
| Название | Applications of carbon nanotubes to electrochemical DNA sensors: a new strategy to make direct and selective hybridization detection from SWNTs |
| Тип | paper |
| DOI | 10.1088/2043-6262/1/4/045011 |
| Electronic ISSN | 2043-6262 |
| Print ISSN | 2043-6254 |
| Журнал | Advances in Natural Sciences: Nanoscience and Nanotechnology |
| Том | 1 |
| Первая страница | 45011 |
| Последняя страница | 45018 |
| Аффилиация | Zhang, Qi Dong; Laboratoire Interfaces-Traitements-Organisation et Dynamique des Systèmes (ITODYS), associé au CNRS-UMR 7086, Université Paris Diderot-Paris 7, 15 rue Jean-Antoine de Baïf, 75205 PARIS cedex 13, France |
| Аффилиация | Piro, Benoît; Laboratoire Interfaces-Traitements-Organisation et Dynamique des Systèmes (ITODYS), associé au CNRS-UMR 7086, Université Paris Diderot-Paris 7, 15 rue Jean-Antoine de Baïf, 75205 PARIS cedex 13, France |
| Аффилиация | Noël, Vincent; Laboratoire Interfaces-Traitements-Organisation et Dynamique des Systèmes (ITODYS), associé au CNRS-UMR 7086, Université Paris Diderot-Paris 7, 15 rue Jean-Antoine de Baïf, 75205 PARIS cedex 13, France |
| Аффилиация | Reisberg, Steeve; Laboratoire Interfaces-Traitements-Organisation et Dynamique des Systèmes (ITODYS), associé au CNRS-UMR 7086, Université Paris Diderot-Paris 7, 15 rue Jean-Antoine de Baïf, 75205 PARIS cedex 13, France |
| Аффилиация | Pham, Minh-Chau; Laboratoire Interfaces-Traitements-Organisation et Dynamique des Systèmes (ITODYS), associé au CNRS-UMR 7086, Université Paris Diderot-Paris 7, 15 rue Jean-Antoine de Baïf, 75205 PARIS cedex 13, France |
| Выпуск | 4 |
