| Автор | Tran, Dai Lam |
| Автор | Le, Van Hong |
| Автор | Pham, Hoai Linh |
| Автор | Hoang, Thi My Nhung |
| Автор | Nguyen, Thi Quy |
| Автор | Luong, Thien Tai |
| Автор | Ha, Phuong Thu |
| Автор | Nguyen, Xuan Phuc |
| Дата выпуска | 2010-12-01 |
| dc.description | This paper presents an overview of syntheses and applications of magnetic nanoparticles (MNPs) at the Institute of Materials Science, Vietnam Academy of Science and Technology. Three families of oxide MNPs, magnetite, manganite and spinel ferrite materials, were prepared in various ways: coprecipitation, sol–gel and high energy mechanical milling. Basic properties of MNPs were characterized by Vibrating Sample Magnetometer (VSM) and Physical Properties Measurement Systems (PPMS). As for biomedical application, the aim was to design a novel multifunctional, nanosized magnetofluorescent water-dispersible Fe<sub>3</sub>O<sub>4</sub>-curcumin conjugate, and its ability to label, target and treat tumor cells was described. The conjugate possesses a magnetic nano Fe<sub>3</sub>O<sub>4</sub> core, chitosan (CS) or Oleic acid (OL) as an outer shell and entrapped curcumin (Cur), serving the dual function of naturally autofluorescent dye as well as antitumor model drug. Fe<sub>3</sub>O<sub>4</sub>-Cur conjugate exhibited a high loading cellular uptake with the help of a macrophage, which was clearly visualized dually by Fluorescence Microscope and Laser Scanning Confocal Microscope (LSCM), as well as by magnetization measurement (PPMS). A preliminary magnetic resonance imaging (MRI) study also showed a clear contrast enhancement by using the conjugate. As for the environmental aspect, the use of magnetite MNPs for the removal of heavy toxic metals, such as Arsenic (As) and Lead (Pb), from contaminated water was studied. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Копирайт | 2010 Vietnam Academy of Science & Technology |
| Название | Biomedical and environmental applications of magnetic nanoparticles |
| Тип | paper |
| DOI | 10.1088/2043-6262/1/4/045013 |
| Electronic ISSN | 2043-6262 |
| Print ISSN | 2043-6254 |
| Журнал | Advances in Natural Sciences: Nanoscience and Nanotechnology |
| Том | 1 |
| Первая страница | 45013 |
| Последняя страница | 45017 |
| Аффилиация | Tran, Dai Lam; Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi , Vietnam |
| Аффилиация | Le, Van Hong; Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi , Vietnam |
| Аффилиация | Pham, Hoai Linh; Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi , Vietnam |
| Аффилиация | Hoang, Thi My Nhung; Faculty of Biology, Hanoi University of Science, Vietnam National University, 334 Nguyen Trai, Hanoi, Vietnam |
| Аффилиация | Nguyen, Thi Quy; Faculty of Biology, Hanoi University of Science, Vietnam National University, 334 Nguyen Trai, Hanoi, Vietnam |
| Аффилиация | Luong, Thien Tai; Faculty of Chemistry, Hanoi National University of Education, 136 Xuan Thuy, Hanoi, Vietnam |
| Аффилиация | Ha, Phuong Thu; Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi , Vietnam |
| Аффилиация | Nguyen, Xuan Phuc; Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi , Vietnam |
| Выпуск | 4 |
