| dc.description |
IT has recently been suggested by Kahlson et al. that the capacity of tissues to form histamine is related to the general process of growth, regeneration and repair<sup>1â 4</sup>. Other workers have cast doubt on this theory, finding little or no histidine decarboxylase activity in various normal and malignant rapidly growing tissues<sup>5â 8</sup>. Telford and West, finding that the optimal conditions for the determination of enzyme activity in the rat vary from tissue to tissue<sup>6,9</sup>, and that the enzyme in different tissues behaves differently from drugs<sup>10</sup>, suggested that in this species there may be several enzymes capable of forming histamine<sup>6</sup>. |
