dc.description |
EXPOSURE to ionizing or ultra-violet radiation or radio-mimetic chemicals has long been known to induce the vegetative reproduction of certain temperate bacterio-phages in lysogenic bacteria<sup>1</sup>. Cytotoxic agents, such as mitomycin C (ref. 2), and folic acid antagonists, such as aminopterin<sup>3</sup>, have also been reported to be inducing agents. Recently, phage induction has been observed after thymine deprivation in lysogenic thymine-deficient mutant strains<sup>4,5</sup>. |