| Автор | Sabesin, Seymour M. |
| Дата выпуска | 1965 |
| dc.description | Small lynmphocytes froni rabbit and guinea pig, grown in tissue culture in the absence of phytohemagglutinin, can transform spontaneously into cytologically immature cells that are indistinguishable morphologically from blast cells. The transformation occurs in 38 to 75 percent of peripheral lymphocytes and 55 to 75 percent of splenic lymphocytes on the 5th day of culture. The altered cells can synthesize RNA and DNA and show mitotic division; synthesis of DNA occurs after the 5th day of culture, whereas RNA is synthesized throughout the duration of culture. |
| Формат | application.pdf |
| Издатель | American Association for the Advancement of Science |
| Копирайт | 1965 by the American Association for the Advancement of Science |
| Тема | REPORTS |
| Название | Lymphocytes of Small Mammals: Spontaneous Transformation in Culture to Blastoids |
| Тип | other |
| Electronic ISSN | 1095-9203 |
| Print ISSN | 0036-8075 |
| Журнал | Science |
| Том | 149 |
| Первая страница | 1385 |
| Последняя страница | 1387 |
| Аффилиация | Department of Medicine, Massachusetts General Hospital, Boston |
| Выпуск | 3690 |
| Библиографическая ссылка | HIRSCHHORN, K, IMMUNE RESPONSE AND MITOSIS OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES IN VITRO, SCIENCE 142: 1185 (1963). |
| Библиографическая ссылка | KOPRIWA, B.M., IMPROVEMENTS IN COATING TECHNIQUE OF RADIOAUTOGRAPHY, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 10: 269 (1962). |
| Библиографическая ссылка | MARSHALL, W.H., GROWTH AND MITOSIS OF HUMAN SMALL LYMPHOCYTES AFTER INCUBATION WITH A PHYTOHAEMAGGLUTININ, QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES 48: 146 (1963). |
| Библиографическая ссылка | NOWELL, P.C., PHYTOHEMAGGLUTININ - AN INITIATOR OF MITOSIS IN CULTURES OF NORMAL HUMAN LEUKOCYTES, CANCER RESEARCH 20: 462 (1960). |
| Библиографическая ссылка | WALKER, R.I., GRANULOCYTE INHIBITION OF HUMAN PERIPHERAL BLOOD LYMPHOCYTE GROWTH IN VITRO, EXPERIMENTAL CELL RESEARCH 38: 379 (1965). |