Автор |
Kroll, Wolfgang A. |
Автор |
Schneider, Jerry A. |
Дата выпуска |
1974 |
dc.description |
The 100-fold increase in free cystine content characteristic of cultured skin fibroblasts from patients with nephropathic cystinosis was decreased more than 50 percent by addition of L-ascorbic acid to the culture medium at concentrations of 0.29 to 2.9 millimolar. Fresh ascorbic acid must be added to the culture medium daily to produce a progressive decrease of the free cystine content of the cells over a 3-day period. Upon removal of ascorbic acid from the medium, the free cystine content returns to its initial value. |
Формат |
application.pdf |
Издатель |
American Association for the Advancement of Science |
Копирайт |
1974 by the American Association for the Advancement of Science |
Тема |
REPORTS |
Название |
Decrease in Free Cystine Content of Cultured Cystinotic Fibroblasts by Ascorbic Acid |
Тип |
research-article |
Electronic ISSN |
1095-9203 |
Print ISSN |
0036-8075 |
Журнал |
Science |
Том |
186 |
Первая страница |
1040 |
Последняя страница |
1042 |
Аффилиация |
Department of Pediatrics, University of California, San Diego, La Jolla 92037 |
Выпуск |
4168 |
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