A Clinical Study of Isolated Aortic Valve Replacement: A Univariate Analysis of Risk Factors
Sung, Kim, Wook; Ryul, Lee, Jeong; Bong, Kim, Ki; Whan, Sung, Sook; Hyuk, Ahn; Jin, Kim, Yong; Hurn, Chae; Hyun, Kim, Joo; Ryang, Rho, Joon; Whan, Kim, Chong; Phill, Suh, Kyung; Kyun, Lee, Young; Sung, Kim, Wook, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Ryul, Lee, Jeong, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Bong, Kim, Ki, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Whan, Sung, Sook, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Hyuk, Ahn, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Jin, Kim, Yong, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Hurn, Chae, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Hyun, Kim, Joo, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Ryang, Rho, Joon, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Whan, Kim, Chong, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Phill, Suh, Kyung, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University; Kyun, Lee, Young, Department of Cardiovascular Surgery, Sejong General Hospital Supported by grants from 1990 SNUH Clinical Research Fund
Журнал:
Asian Cardiovascular and Thoracic Annals
Дата:
1993
Аннотация:
Between 1979 and 1990, 190 patients underwent isolated aortic valve replacement at Seoul National University Hospital in Korea. There were 11 (5.8%) in-hospital deaths. Univariate analysis identified advanced age (p = 0.026), preoperative serum GOT or GPT greater than 40 IU/1 (p < 0.001, p = 0.003), NYHA Class III or IV (p = 0.029), preoperative mean pulmonary arterial pressure greater than 19 mmHg (p = 0.019), reoperation for aortic valve replacement (p = 0.035), second or third open heart surgery (p < 0.001), and use of mechanical valve (p = 0.008) as variables associated with increased in-hospital risk. Follow-up documented survival rates of 98.1% and 96.4% and event-free survival rates of 95.7% and 81.6% at 3 and 7 postoperative years, respectively. NYHA Class III or IV (p = 0.009), preoperative serum total bilirubin level greater than 1.2 mg/dl (p = 0.009), reoperation for aortic valve replacement (p = 0.03), second or third open heart surgery (p = 0.002), and use of mechanical valve were associated with decreased late survival and event-free survival.
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