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Автор Heck, Albert, F.
Дата выпуска 1989
dc.description Mitral valve prolapse (MVP), the most frequently encountered valvular condition in the population, has been reported in an increasing variety of neurologic, muscular, and psychiatric disorders during the last twelve years. Extensive review of reports indicates this has resulted from observations of either (1) inordinate incidence of MVP in well-defined neurologic entities or (2) development of neurologic or ophthalmologic complications attributed to MVP. In the review presented, basis is found for categorizing MVP by its association with (1) well-defined, genetically determined neurologic disorders; (2) disorders characterized by structural abnormalities, many genetically determined, or inflammatory processes of connective tissues; (3) "mechanical" prolapse resulting from disproportion of mitral valve annulus and left ventricular size, which is, at times, reversible; and (4) a generally asymptomatic state that, at times, is associated with ischemic, thrombotic, embolic, and infectious disorders of the brain and eye. The paradox between the large number of persons with MVP in the general population who remain healthy and a subpopulation of patients with complications of MVP (eg, stroke) or other entities has been identified. A second paradox is found between the well-known increased incidence of MVP, especially in young patients with stroke, and the apparent rarity of stroke among patients with both common (eg, migraine) and unusual (eg, myotonic dystrophy) neurologic entities in which an extraordinary high prevalence of MVP is known to exist.
Издатель Sage Publications
Название 35th Annual Meeting — American College of Angiology Orlando, Florida — October, 1988 Symposium Proceedings
Тип Journal Article
DOI 10.1177/000331978904000810
Print ISSN 0003-3197
Журнал Angiology
Том 40
Первая страница 743
Последняя страница 751
Аффилиация Heck, Albert, F., Department of Neurology, West Virginia University School of Medicine, Charleston Division, and Charleston Area Medical Center, Charleston, West Virginia
Выпуск 8
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