| Автор | Martin, Michael |
| Автор | Heimig, Thomas |
| Автор | Othmar Fiebach, B.J. |
| Автор | Magnus, Lothar |
| Автор | Riedel, Christa |
| Дата выпуска | 1994 |
| dc.description | Lysis block treatment (LBT) is a new form of fibrinolytic therapy for deep vein thrombosis and arterial occlusion in the distal parts of the limbs. Strictly local lysis was achieved by placing a cuff around the thigh or the upper arm, inflating the cuff to a pressure of 500 mmHg ("Bier's blockade"), and giving heparin and tissue plasminogen activator (rt-PA) by intravenous injection into the dorsal pedis or antecubital veins. Occlusion lasted for one hour. This new technique was demonstrated in 22 patients. Six patients presented with popliteal vein thromboses and 1 patient with a distal femoral vein thrombosis. In addi tion, 15 arterial occlusions were treated comprising 3 calf, 6 popliteal, 3 distal femoral, and 2 digital sites and 1 brachial site. Five of 7 venous and 9 of 15 arterial occlusions were partially or totally removed. The activated partial thromboplastin time remained nearly unchanged during LBT and only a limited and short-term lengthening was recorded after restoration of blood flow. This was of importance for patients with bleeding tendencies, which are normally a contraindication for systemic lysis. LBT may therefore be considered as a useful alternative to systemic fibrinolytic treatment. |
| Издатель | Sage Publications |
| Название | Lysis Block Treatment: A New Form of Local Thrombolysis |
| Тип | Journal Article |
| DOI | 10.1177/000331979404500210 |
| Print ISSN | 0003-3197 |
| Журнал | Angiology |
| Том | 45 |
| Первая страница | 143 |
| Последняя страница | 148 |
| Аффилиация | Martin, Michael, Geriatric Department, Städitsche Kliniken |
| Аффилиация | Heimig, Thomas, Geriatric Department, Städitsche Kliniken |
| Аффилиация | Othmar Fiebach, B.J., Radiology Department, Städtische Kliniken, Duisburg 1 Germany |
| Аффилиация | Magnus, Lothar, Radiology Department, Städtische Kliniken, Duisburg 1 Germany |
| Аффилиация | Riedel, Christa, Geriatric Department, Städitsche Kliniken |
| Выпуск | 2 |
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