Издательство SAGE Publications по журналам "Journal of Biomolecular Screening"
Отображаемые элементы 1-20 из 105
-
(Sage Publications, 1996-02-01)
-
(Sage Publications, 1997-02-01)
-
(Sage Publications, 1997-03-01)
-
(Sage Publications, 1997-04-01)
-
(Sage Publications, 1996-06-01)
-
(Sage Publications, 1998-04-01)
-
(Sage Publications, 1997-06-01)
-
(Sage Publications, 1998-03-01)
-
(Sage Publications, 1998-02-01)
-
(Sage Publications, 1998-04-01)We report the successful miniaturization of a functional cell-based reporter gene assay. Utilizing interleukin-1beta (IL-1/)-induced secreted placental alkaline phosphatase (SPAP)-catalyzed colorimetric readout, we reduced ...
-
(Sage Publications, 1996-06-01)Simultaneous 96-well pipetting is an integral procedure in high throughput screening (HTS). There are several automated 96-well pipettors in the marketplace today. Inherent to any successful HTS assay is an understanding ...
-
(Sage Publications, 1996-04-01)Combinatorial chemistry has opened a new realm of chemical diversity in the search for useful therapeutics as well as the ability to generate chemical libraries of hundreds of thousands to millions of discrete compounds. ...
-
(Sage Publications, 1997-06-01)A 96-well enzyme-linked immunosorbent assay was developed to discover compounds that inhibit the binding of the Leu-X-Cys-X-Glu (LXCXE) motif to the retinoblastoma tumor suppressor protein (pRB). The assay uses a ...
-
(Sage Publications, 1996-06-01)
-
(Sage Publications, 1997-02-01)Binding of a protein at a ligand-modified ion channel can lead to closure or distortion of the channel, resulting in a digital on/off response of the ion flux. This principle could be applied as a strategy for sensor design ...
-
(Sage Publications, 1997-04-01)The rapid identification of the bioactive component(s) of natural product mixtures in high throughput screening programs has become a critical factor to ensure that this source of diverse chemotypes can compete effectively ...
-
(Sage Publications, 1998-06-01)Developments in high throughput screening (HTS) have led to new needs in automation to enable better handling of applications such as homogeneous assays and cherry picking. Software and hardware integration approaches for ...
-
(Sage Publications, 1998-03-01)A program has been written to transfer a set of discontinuous samples in 96-well storage plates to archival plates using an 80-well format. One thousand samples per day can be processed in this manner. The software can ...
-
(Sage Publications, 1996-02-01)
-
(Sage Publications, 1998-04-01)Novel analytical techniques are demanded in parallel in the automated combinatorial library syntheses for accelerating the process of drug discovery. In this study, the integration of matrix-assisted laser desorption ...
Отображаемые элементы 1-20 из 105