A Case of Fatal Endrin Poisoning
Runhaar, E.A.; Sangster, B.; Greve, P.A.; Voortman, M.; Runhaar, E.A., National Institute of Public Health and Environmental Hygiene, PO Box 1, 3720 BA Bilthoven, Department of Reanimation and Clinical Toxicology, University Hospital Utrecht, Catharijnesingel 101, 3500 CG Utrecht; Sangster, B., National Institute of Public Health and Environmental Hygiene, PO Box 1, 3720 BA Bilthoven, Department of Reanimation and Clinical Toxicology, University Hospital Utrecht, Catharijnesingel 101, 3500 CG Utrecht; Greve, P.A., National Institute of Public Health and Environmental Hygiene, PO Box 1, 3720 BA Bilthoven; Voortman, M., State Laboratory Forensic Pathology, Volmerlaan 17, 2288 GD Rijswijk, The Netherlands
Журнал:
Human and Experimental Toxicology
Дата:
1985
Аннотация:
1 Ingestion of 12 g of endrin by a 49-year-old man caused convulsions persisting for 4 days, hypersalivation, hyperthermia, renal insufficiency, thrombocytopenia and recurrent hypotension. Death followed after 11 days, due to pulmonary complications (infection and haemorrhage) and hypoxaemia causing bradycardia and cardiac arrest.2 Endrin and dieldrin concentrations in blood 4 hours, 6 and 11 days after ingestion were respectively 450, 86 and 71 μg/l for endrin and 60, 19 and 19 μg/l for dieldrin. Dieldrin was also present, possibly because the endrin preparation contained traces of dieldrin.3 Endrin concentrations 11 days after ingestion were 0.071 mg/l in blood, in adipose tissue 89.5 mg/kg, in the heart 0.87 mg/kg, in the brain 0.89 mg/kg, in the kidneys 0.55 mg/kg and in the liver 1.32 mg/kg.
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