| Автор | Yoshida, M. |
| Автор | Shimada, E. |
| Автор | Yamanaka, S. |
| Автор | Aoyama, H. |
| Автор | Yamamura, Y. |
| Автор | Owada, S. |
| Дата выпуска | 1987 |
| dc.description | A 56-year-old male attempted suicide by ingestion of about 60 ml of 50% fenitrothion (Sumithion) emulsion. Five hours later, combined hemoperfusion and hemodialysis (HP-HD) treatment was performed for 60 min and consequently the toxic symptoms improved gradually. However, cholinergic symptoms recurred 4 days after ingestion. Although HP-HD was immediately performed for 180 min, it had no effect on the clinical symptoms. He died of respiratory insufficiency 6 days after the ingestion of fenitrothion.Fenitrothion concentration in the organs and tissues showed the highest values in the fat tissue, followed in decreasing order by the pancreas, muscle, lung and brain. The results indicate that fenitrothion has high lipid solubility and deposits in the fat tissue. Furthermore, we believe that when HP-HD therapy is used in the treatment of acute insecticide poisoning it is important that it be performed continuously and in as early a stage as possible. |
| Издатель | Sage Publications |
| Название | A Case of Acute Poisoning with Fenitrothion (Sumithion) |
| Тип | Journal Article |
| DOI | 10.1177/096032718700600511 |
| Print ISSN | 0960-3271 |
| Журнал | Human and Experimental Toxicology |
| Том | 6 |
| Первая страница | 403 |
| Последняя страница | 406 |
| Аффилиация | Yoshida, M., Departments of Public Health, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 213 |
| Аффилиация | Shimada, E., Departments of Public Health, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 213 |
| Аффилиация | Yamanaka, S., Department of Hygiene, Tokyo Dental College, 1-2-2 Masago, Chiba 260, Japan |
| Аффилиация | Aoyama, H., Departments of Public Health, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 213 |
| Аффилиация | Yamamura, Y., Departments of Public Health, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 213 |
| Аффилиация | Owada, S., Internal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 213 |
| Выпуск | 5 |
| Библиографическая ссылка | Ecobichon DJ , Ozere RL, Reid E. & Crocker Jfs. Acute fenitrothion poisoning. Canadian Medical Association Journal 1977; 116: 377-9. |
| Библиографическая ссылка | Sakamoto T., Sawada Y., Nishida K., et al. Delayed neuro-toxicity produced by an organophosphorous compound (Sumithion), Archives of Toxicology1984; 56: 136-8. |
| Библиографическая ссылка | Shimada E., Yoshida M., Yamanaka Y., Aoyama H. & Yamamura Y. Erythrocyte and plasma cholinesterase activity on poisoning of disyston, fenitrothion and malathion. Japanese Journal of Industrial Health 1986; 28: 368-9. (in Japanese) |
| Библиографическая ссылка | Okonek S.Probable progress in the therapy of organophosphate poisoning—extracorporeal hemodialysis and hemoperfusion. Archives of Toxicology1976; 35: 221-7. |
| Библиографическая ссылка | Voss G. & Sachsse K. Red cell and plasma cholinesterase activity in micro samples of human and animal blood determined simultaneously by a modified acetylthiocholine/DTNB procedure, Toxicology and Applied Pharmacology, 1970; 16: 764-72. |
| Библиографическая ссылка | Lawford DJ & Harvey DG Determination of p-nitrophenol in urine and in blood by indophenol reaction . Analyst 1953; 78: 63-5. |
| Библиографическая ссылка | Sasaki Y.Study on salivary secretion and fenitrothion concentration in saliva of rats treated with fenitrothion-[O,O-dimethyl-O-(3-methyl-4-nitrophenyl) phosphorothioate] . Shika Gakuho 1982; 82: 253-69. (in Japanese) |
| Библиографическая ссылка | Okonek S., Tonnis HJ, Baldamus CA & Hoffmann A. Hemoperfusion versus hemodialysis in the management of patients severely poisoned by organophosphorus insecticides and bipyridyl herbicides. Artificial Organs 1979; 3: 341-5. |
| Библиографическая ссылка | Miyamoto J., Sato Y., Kadota T., Fujinami A. & Endo M. Part I . Metabolic fate of 32P labeled sumithion and methylparathion in guinea pig and white rat, Agricultural and Biological Chemistry Journal 1963; 27: 381-9. |
| Библиографическая ссылка | Davies JE, Barquet A., Freed VH, et al. Human pesticide poisoning by a fat-soluble organophosphate insecticide . Archives of Environmental Health 1975; 30: 608-13. |
