31P in-Vivo Spectroscopic Study by High-Field Whole-Body MR System—An Application to a Case with Arteriosclerosis Obliterans

Abstract

31P in-vivo spectroscopy was performed by a 1.5-tesla whole-body MR sys tem. The 31P spectrum for the calf muscle in a patient with arteriosclerosis obli terans having intermittent claudication was obtained every two minutes. When the spectrum after the workload was compared with that at rest, an increase in inorganic phosphate (Pi) and a decrease in phosphocreatine (PCr) were ob served, resulting in a strong decrease in the PCr/Pi ratio. This method can measure the ischemic and recovery stages of energy metabolism in skeletal mus cle noninvasively and continuously in addition to magnetic resonance imaging.