Автор |
Wyckoff, P.M. |
Автор |
Miller, L.C. |
Автор |
Tucker, L.B. |
Автор |
Schaller, J.G. |
Дата выпуска |
1995 |
dc.description |
Neuropsychological assessments of adults with SLE have shown cognitive impairment, sequential processing deficits, memory loss, increased incidence of left handedness, learning disabilities and emotional distress compared with healthy individuals or subjects with other medical conditions. Neuropsychological testing regarding these variables in children and adolescents with SLE has been infrequently reported. For this study, eight children with SLE (age 9-17 years at diagnosis) were assessed with neuropsychological testing at a median of 10.5 months (range 1 week to 30 months) after diagnosis. Tests included Wechsler Intelligence Scale for Children-Revised or Wechsler Adult Intelligence Scale-Revised, Wide Range Achievement Test-Revised, Standard Binet Intelligence Scale Fourth Edition Memory Subtests or Wechsler Memory Scale (all mean = 100 ± 15) and Gates MacInitie Reading Comprehension Test, Achenbach Child Behavior Checklist and Achenbach Youth Self Report. Mean intellectual scores were in the low average range (Wechsler Full Scale mean = 85.0 ± 11.9, Verbal Scale mean 85.2 ± 13.9, Performance Scale mean = 88.0 ± 13.9). Academic achievement was globally depressed (reading recognition mean = 79.5 ± 22.0, spelling mean = 78.9 ± 23.5), especially in arithmetic (mean = 70.5 ± 14.9). Children with SLE averaged 5 years behind grade placement in reading comprehension. Visual memory was also depressed in patients with SLE. Behavior ratings failed to demonstrate any significant aberrations in the test subjects. |
Издатель |
Sage Publications |
Тема |
pediatrics |
Тема |
neuropsychology |
Название |
Neuropsychological assessment of children and adolescents with systemic lupus erythematosus |
Тип |
Journal Article |
DOI |
10.1177/096120339500400310 |
Print ISSN |
0961-2033 |
Журнал |
Lupus |
Том |
4 |
Первая страница |
217 |
Последняя страница |
220 |
Аффилиация |
Wyckoff, P.M., Divisions of Neurology and Rheumatology, Department of Pediatrics, The Floating Hospital for Children, New England Medical Center, 750 Washington Street, Boston, MA 02111, USA |
Аффилиация |
Miller, L.C., Divisions of Neurology and Rheumatology, Department of Pediatrics, The Floating Hospital for Children, New England Medical Center, 750 Washington Street, Boston, MA 02111, USA |
Аффилиация |
Tucker, L.B., Divisions of Neurology and Rheumatology, Department of Pediatrics, The Floating Hospital for Children, New England Medical Center, 750 Washington Street, Boston, MA 02111, USA |
Аффилиация |
Schaller, J.G., Divisions of Neurology and Rheumatology, Department of Pediatrics, The Floating Hospital for Children, New England Medical Center, 750 Washington Street, Boston, MA 02111, USA |
Выпуск |
3 |
Библиографическая ссылка |
Yancey C., Doughty R., Athreya B.Central nervous system involvement in childhood systemic lupus erythematosus . Arthritis Rheum 1981; 24: 1389-1395. |
Библиографическая ссылка |
Kozora E., Thompson L., Cullum C.A pilot study evaluating neuropsychological and psychological status of patients with systemic lupus erythematosus. J Clin Exper Neuropsochol1922; 14: 101. |
Библиографическая ссылка |
Denburg S. et al. Neuropsychological correlates of serum lymphocytotoxic antibodies in systemic lupus erythematosus. Brain Behav Immun 1988; 2: 222-234. |
Библиографическая ссылка |
Lahita R.Systemic lupus erythematosus: learning disability in the male offspring of female patients and relationship to laterality. Psychoneuroendocrinology1988; 13: 385-396. |
Библиографическая ссылка |
Geschwind N. , Behan P. Lefthandedness: association with immune disease, migraine and developmental learning disorder. Proc Natl Acad Sci USA 1982; 79: 5097-5100. |
Библиографическая ссылка |
Magner MBPsychiatric morbidity in outpatients with systemic lupus erythematosus. S Afr Med J1991; 80: 291-293. |
Библиографическая ссылка |
Barron KS et al. Clinical, serologic and immunogenetic studies in childhood onset systemic lupus erythematosus. Arthritis Rheum 1993; 36: 348-354. |
Библиографическая ссылка |
Tan EM et al. The 1982 revised criteria for classification of systemic lupus erythematosus (SLE). Arthritis Rheum 1982; 25: 1271-1277. |
Библиографическая ссылка |
Papero PH et al. Neuropsychological deficits and antineuronal antibodies in pediatric systemic lupus erythematosus. Clin Exp Rheum 1990; 8: 4 17-424. |
Библиографическая ссылка |
Ryan C., Vega A., Drash A.Cognitive deficits in adolescents who developed diabetes early in life. Pediatrics1985; 75: 921-927. |