| Автор | Massaro, A, R |
| Дата выпуска | 1998 |
| dc.description | Knowing the mechanisms and the times of remyelination is not only an intriguing scientific challenge but it has also important consequences on the therapeutic approach to multiple sclerosis (MS). The neural-cell adhesion molecule (N-CAM) shows tempting suggestions about its possible involvement in reparative mechanisms, and, finally, in remyelination. In fact, its levels progressively increase in the cerebrospinal fluid (CSF) of acute MS patients, paralleling the progressive clinical improvement after the attack. Some information is also given about the ciliary neurotrophic factor (CNTF), whose CSF levels were found to be increased in MS patients who were recovering from an acute exacerbation. |
| Издатель | Sage Publications |
| Тема | multiple sclerosis |
| Тема | cerebrospinal fluid |
| Тема | remyelination |
| Тема | biological markers |
| Тема | N-CAM |
| Тема | CNTF |
| Тема | S-100 |
| Название | Are there indicators of remyelination in blood or CSF of multiple sclerosis patients? |
| Тип | Journal Article |
| DOI | 10.1177/135245859800400326 |
| Print ISSN | 1352-4585 |
| Журнал | Multiple Sclerosis |
| Том | 4 |
| Первая страница | 228 |
| Последняя страница | 231 |
| Аффилиация | Massaro, A, R, Institute of Neurology, UCSC Medical School, 00168 Rome, Italy |
| Выпуск | 3 |
| Библиографическая ссылка | Greenfield JG, King LS. (1958) Demyelinating diseases. In: Greenfield JGet al. (eds). Greenfield's Neuropathology. London: Edward Arnold pp. 441-474. |
| Библиографическая ссылка | Lumsden CE. (1970) The neuropathology of multiple sclerosis. In: Vinken PJ & Bruyn GW (eds). Handbook of Clinical Neurology, vol. 9. Amsterdam: North-Holland PC pp. 217-309. |
| Библиографическая ссылка | Prineas JWet al. (1993) Multiple sclerosis: remyelination of nascent lesion. Ann Neurol 33: 137-151. |
| Библиографическая ссылка | Ozawa Ket al. (1994) Patterns of oligodendroglia pathology in multiple sclerosis. Brain 117: 1311-1322. |
| Библиографическая ссылка | Edelman GM. (1986) Cell adhesion molecules in the regulation of animal form and tissue pattern. Ann Rev Cell Biol 2: 81-116. |
| Библиографическая ссылка | Cioffi RP, Carbone G, Massaro AR. (1986) Alcuni aspetti neurobiologici della N-CAM. Arch Psicol Neurol Psich 47: 191-208. |
| Библиографическая ссылка | Bock E, Edvardsen K, Linneman D, Nybroe O. (1988) Structure and function of soluble NCAM. In: Gorio A, Perez-Polo JR, de Vellis J, Haber B (eds). Neural Development and Regeneration. Berlin-Heidelberg: Springer-Verlag pp. 343-352. |
| Библиографическая ссылка | Bath S, Silberberg DH. (1986) Oligodendrocyte cell adhesion molecules are related to N-CAM. JNeurosci 6: 3348-3354. |
| Библиографическая ссылка | Bath S, Silberberg DH. (1988) N-CAM 180, the largest component of the N-CAM, is reduced in dysmyelinating quaking mutant mouse brain. Brain Res 452: 373-377. |
| Библиографическая ссылка | Bath S, Silberberg DH. (1988) Developmental expression of N-CAM of oligodendrocytes in vivo and in culture. J Neurochem 50: 1830-1838. |
| Библиографическая ссылка | Ono Jet al. (1994) Central nervous system abnormalities in chromosome deletion at 11q23. Clin Genet 45: 325-329. |
| Библиографическая ссылка | Montag Det al. (1994) Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin. Neuron 13: 229-246. |
| Библиографическая ссылка | Tacke R & Martini R. (1990) Changes in expression of mRNA specific for cell adhesion molecules (L1 and N-CAM) in the transected peripheral nerve of the adult rat. Neuroscience Letters 120: 227-230. |
| Библиографическая ссылка | Nait Oumesmar Bet al. (1995) Expression of the highly polysialylated neural cell adhesion molecule during postnatal and following chemically induced demyelination of the adult mouse spinal cord. Europ J Neurosci 7: 480-491. |
| Библиографическая ссылка | Massaro AR, Scivoletto G, Tonali P. (1990) Cerebrospinal fluid markers in neurological disorders. It J Neurol Sci 11: 537-547. |
| Библиографическая ссылка | Massaro AR, Albrechtsen M, Bock E. (1987) N-CAM in CSF: a marker of synaptic remodelling after acute phases of multiple sclerosis? It J Neurol Sci s6: 85-88. |
| Библиографическая ссылка | Ibsen S, Berezin V, Nùrgaard Pedersen B, Bock E. (1983) Enzyme-linked immunosorbent assay of the D2 glyco-protein. J Neurochem 41: 356-362. |
| Библиографическая ссылка | Massaro AR, Albrechtsen M, Bock E. (1987) Determination of the neural-cell adhesion molecule (N-CAM) in cerebrospinal fluid from patients with multiple sclerosis. In: Lowenthal A & Raus J (eds). Cellular and Humoral Immunological Components of Cerebrospinal Fluid in Multiple Sclerosis. New York: Plenum PC pp. 397-402. |
| Библиографическая ссылка | Massaro ARet al. (1985) Myelin basic protein and S-100 antigen in cerebrospinal fluid of patients with multiple sclerosis in the acute phase. It J Neurol Sci 6: 53-56. |
| Библиографическая ссылка | Massaro AR.La sclerosi multipla. In: Bergonzi P & Massaro AR (eds). Trattato Italiano di Neurologia, vol. 4. Roma: Verduci Editore (in press). |
| Библиографическая ссылка | Massaro AR, Carnevale A, Tonali P, Bock E. (1997) Glial cell pathobiology in multiple sclerosis detected by CSF markers. In: Teelken AW & Korf J (eds). Neurochemistry. New York: Plenum PC pp. 451-455. |
| Библиографическая ссылка | Massaro AR & Tonali P. (1998) Cerebrospinal fluid markers in multiple sclerosis: an overview. Multiple Sclerosis 4: 1-4. |
| Библиографическая ссылка | Massaro AR, Cioffi R, Carbone G. (1988) Serum and cerebrospinal fluid levels of N-CAM in multiple sclerosis patients. Europ J Neurosci s1: 328-328. |
| Библиографическая ссылка | Louis J-C, Magal E, Takayama S, Varon S. (1993) CNTF protection of oligodendrocytes against natural and tumor necrosis factor induced death. Science 259: 689-692. |
| Библиографическая ссылка | D'Souza S, Alinauskas K, Antel JP. (1996) Ciliary neurotrophic factor selectively protects human oligodendrocytes from tumor necrosis factor-mediated injury. J Neurosci Res 43: 289-298. |
| Библиографическая ссылка | Winter CG, Saotome Y, Levison SW, Hirsh D. (1995) A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury. Proc Natl Acad Sci USA 92: 5865-5869. |
| Библиографическая ссылка | Smith GM, Rabinovsky ED, McManaman JL, Shine HD. (1993) Temporal and spatial expression of ciliary neurotrophic factor after peripheral nerve injury. Exp Neurol 121: 239-247. |
| Библиографическая ссылка | Massaro AR, Soranzo C, Carnevale A. (1997) Cerebro-spinal fluid ciliary neurotrophic factor (CNTF) in neurological patients. Europ Neurol 37: 243-246. |
| Библиографическая ссылка | Massaro ARet al. (1997) Neurotrophic factors in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases. In: Abramski O & Ovadia H (eds). Frontiers in Multiple Sclerosis. London: Martin Dunitz Publisher pp. 155-160. |
