During a 7-year period, 44 patients were treated for bladder calculi in our tertiary-care hospital. The rate of bladder calculi was 11 per 1, 000 admissions to the Physical Medicine and Rehabilitation Service and 16 per 1, 000 admissions to the Urology Service. The two major risk factors were neurological disorders (particularly spinal cord injury), occurring in 30 of 44 cases (68%), and bladder outlet obstruction, occurring in 9 cases (13%). The most common clinical presentations were urinary tract infection (59%), particularly with urease-producing organisms, urinary obstruction (14%), passage of gravel (11%), and hematuria (9%). Most patients were treated successfully with endoscopic methods with minimal morbidity. Bladder calculi remain a treatable cause of morbidity in patients with neurological diseases and bladder outlet obstruction.